Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29849592
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Gastroenterol+Res+Pract
2018 ; 2018
(ä): 5480961
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The Value of Fecal Microbiota Transplantation in the Treatment of Ulcerative
Colitis Patients: A Systematic Review and Meta-Analysis
#MMPMID29849592
Cao Y
; Zhang B
; Wu Y
; Wang Q
; Wang J
; Shen F
Gastroenterol Res Pract
2018[]; 2018
(ä): 5480961
PMID29849592
show ga
BACKGROUND AND AIMS: Fecal microbiota transplantation (FMT) has challenged the
traditional management of ulcerative colitis (UC) in recent years, while it
remained controversial. We aimed to provide a systematic protocol of FMT
treatment on UC. METHODS: Studies reporting on FMT treatment in UC patients were
performed. A fixed-effect model was used to assess the efficacy of FMT. RESULTS:
Eighteen studies were enrolled (n = 446). A pooled proportion of patients who
received FMT had a significant efficacy compared to the placebo group (odds ratio
(OR): 2.73, P = 0.002) with a low risk of heterogeneity (P = 0.59, I(2) = 0%).
The Mayo score decreased to 5 points in a state of mild-moderate activity after
FMT treatment, and the optimal range of the Mayo score baseline was 6-9 for FMT
administration. Then, the baseline of the Shannon diversity index (SDI) had a
negative correlation with the clinical response rate (R = -0.992, P = 0.08) or
remission rate (R = -0.998, P = 0.036), and the optimal diversity of bacteria was
at 7 days to one month. Moreover, the colonoscopy delivery and unrelated fecal
donor had slight superiorities of FMT treatment. CONCLUSION: FMT treatment had a
higher efficacy and shorter time-point of early assessment of effectiveness on UC
patients compared to traditional therapies. And the optimal FMT delivery and
donor were colonoscopy delivery and unrelated donor in clinical practice.