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10.1155/2018/3024698 http://scihub22266oqcxt.onion/10.1155/2018/3024698 C5903307!5903307!29850501     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Res+Int 2018 ; 2018 (ä): ä Nephropedia Template TP {{tp|p=29850501|t=2018. Urine Trefoil Factors as Prognostic Biomarkers in Chronic Kidney Disease |pdf=|usr=}}{{29850501}} gab.com Text Urine Trefoil Factors as Prognostic Biomarkers in Chronic Kidney Disease JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=29850501 #FOAvip Introduction: Trefoil factor family (TFF) peptides are increased in serum and urine in patients with chronic kidney disease (CKD). However, whether the levels of TFF predict the progression of CKD remains to be elucidated. Methods: We determined the TFF levels using peptide-specific ELISA in spot urine samples and performed a prospective cohort study. The association between the levels of urine TFFs and other urine biomarkers as well as the renal prognosis was analyzed in 216 CKD patients (mean age: 53.7 years, 47.7% female, 56.9% with chronic glomerulonephritis, and mean eGFR: 58.5?ml/min/1.73?m2). Results: The urine TFF1 and TFF3 levels significantly increased with the progression of CKD stages, but not the urine TFF2 levels. The TFF1 and TFF3 peptide levels predicted the progression of CKD ? stage 3b by ROC analysis (AUC 0.750 and 0.879, resp.); however, TFF3 alone predicted CKD progression in a multivariate logistic regression analysis (odds ratio 3.854, 95% confidence interval 1.316?11.55). The Kaplan-Meier survival curves demonstrated that patients with a higher TFF1 and TFF3 alone, or in combination with macroalbuminuria, had a significantly worse renal prognosis. Conclusion: The data suggested that urine TFF peptides are associated with renal progression and the outcomes in patients with CKD. Twit Text FOAVip Urine Trefoil Factors as Prognostic Biomarkers in Chronic Kidney Disease ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=29850501 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29850501 #FOAvip English Wikipedia <ref>{{Cite pmid|29850501}}</ref> Urine Trefoil Factors as Prognostic Biomarkers in Chronic Kidney Disease #MMPMID29850501 Yamanari T; Sugiyama H; Tanaka K; Morinaga H; Kitagawa M; Onishi A; Ogawa-Akiyama A; Kano Y; Mise K; Ohmoto Y; Shikata K; Wada J Biomed Res Int 2018[]; 2018 (ä): ä PMID29850501show ga Introduction: Trefoil factor family (TFF) peptides are increased in serum and urine in patients with chronic kidney disease (CKD). However, whether the levels of TFF predict the progression of CKD remains to be elucidated. Methods: We determined the TFF levels using peptide-specific ELISA in spot urine samples and performed a prospective cohort study. The association between the levels of urine TFFs and other urine biomarkers as well as the renal prognosis was analyzed in 216 CKD patients (mean age: 53.7 years, 47.7% female, 56.9% with chronic glomerulonephritis, and mean eGFR: 58.5?ml/min/1.73?m2). Results: The urine TFF1 and TFF3 levels significantly increased with the progression of CKD stages, but not the urine TFF2 levels. The TFF1 and TFF3 peptide levels predicted the progression of CKD ? stage 3b by ROC analysis (AUC 0.750 and 0.879, resp.); however, TFF3 alone predicted CKD progression in a multivariate logistic regression analysis (odds ratio 3.854, 95% confidence interval 1.316?11.55). The Kaplan-Meier survival curves demonstrated that patients with a higher TFF1 and TFF3 alone, or in combination with macroalbuminuria, had a significantly worse renal prognosis. Conclusion: The data suggested that urine TFF peptides are associated with renal progression and the outcomes in patients with CKD. äUrine Trefoil Factors as Prognostic Biomarkers in Chronic Kidney Disea(epmc).pdf DeepDyve Pubget Overpricing