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10.1186/s12969-018-0242-0 http://scihub22266oqcxt.onion/10.1186/s12969-018-0242-0 C5902884!5902884 !29661199     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29661199 &cmd=llinks): Failed to open stream: HTTP request failed! 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Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate |pdf=|usr=}}{{29661199 }} gab.com Text Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate JO: Pediatr Rheumatol Online J http://www.kidney.de/pget.php?&tw=1&pmid=29661199 #FOAvip BACKGROUND: Pregnant women with systemic lupus erythematosus (SLE) have increased risk of adverse outcomes including disease flare, spontaneous abortion, preeclampsia/eclampsia, premature birth and maternal death. However, pregnancy outcomes among adolescents and young women with SLE have not been well-explored. Our objective was to compare risk of adverse pregnancy outcomes in adolescents and young women with SLE to risk among peers without SLE. METHODS: We studied the 2000-2011 Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) to estimate the prevalence of adverse pregnancy outcomes in women with SLE aged ??21 years at time of delivery. Outcomes were compared to peers without SLE by using multivariate logistic regression to calculate odds ratios and risk differences. Additionally, differences in length of stay and total charges per hospitalization were described. RESULTS: There were 8,791,391 unique pregnancies, of which 4002 occurred in young women with SLE. After adjustment for age, race, insurance type and quartile of median income based on patient ZIP code individuals with SLE had increased odds of pre-eclampsia/eclampsia (OR 3.2, 95% CI 2.3-4.6), maternal death (OR 80, 95% CI 10-604), preterm birth (OR 2.7, 95% CI 2-3.7), spontaneous abortion (OR 5.1, 95% CI 2.8-9.6), and induced abortion (OR 30, 95% CI 14-63). The increase in risk among women with SLE was greatest for preterm birth (RD 11%, 95% CI 6-16), pre-eclampsia/eclampsia (RD 9%, 95% CI 5-13), and spontaneous abortion (RD 4%, 95% CI 0.9-6). Risk difference for induced abortion was 2% with 95% CI 0.6-4, while the difference in risk for maternal death did not reach statistical significance (RD 0.4, 95% CI -0.4-1). CONCLUSIONS: Adolescents and young women with SLE experience increased risk of adverse, pregnancy-specific outcomes as compared to their peers, including pre-eclampsia/eclampsia, maternal death, preterm birth, spontaneous abortion, and induced abortion. Additionally, length of stay and total charges for hospitalization are increased. Twit Text FOAVip Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate ????Pediatr Rheumatol Online J http://www.kidney.de/pget.php?&tw=1&pmid=29661199 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29661199 #FOAvip English Wikipedia <ref>{{Cite pmid|29661199 }}</ref> Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate #MMPMID29661199 Ling N ; Lawson E ; von Scheven E Pediatr Rheumatol Online J 2018[Apr]; 16 (1 ): 26 PMID29661199 show ga BACKGROUND: Pregnant women with systemic lupus erythematosus (SLE) have increased risk of adverse outcomes including disease flare, spontaneous abortion, preeclampsia/eclampsia, premature birth and maternal death. However, pregnancy outcomes among adolescents and young women with SLE have not been well-explored. Our objective was to compare risk of adverse pregnancy outcomes in adolescents and young women with SLE to risk among peers without SLE. METHODS: We studied the 2000-2011 Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) to estimate the prevalence of adverse pregnancy outcomes in women with SLE aged ??21 years at time of delivery. Outcomes were compared to peers without SLE by using multivariate logistic regression to calculate odds ratios and risk differences. Additionally, differences in length of stay and total charges per hospitalization were described. RESULTS: There were 8,791,391 unique pregnancies, of which 4002 occurred in young women with SLE. After adjustment for age, race, insurance type and quartile of median income based on patient ZIP code individuals with SLE had increased odds of pre-eclampsia/eclampsia (OR 3.2, 95% CI 2.3-4.6), maternal death (OR 80, 95% CI 10-604), preterm birth (OR 2.7, 95% CI 2-3.7), spontaneous abortion (OR 5.1, 95% CI 2.8-9.6), and induced abortion (OR 30, 95% CI 14-63). The increase in risk among women with SLE was greatest for preterm birth (RD 11%, 95% CI 6-16), pre-eclampsia/eclampsia (RD 9%, 95% CI 5-13), and spontaneous abortion (RD 4%, 95% CI 0.9-6). Risk difference for induced abortion was 2% with 95% CI 0.6-4, while the difference in risk for maternal death did not reach statistical significance (RD 0.4, 95% CI -0.4-1). CONCLUSIONS: Adolescents and young women with SLE experience increased risk of adverse, pregnancy-specific outcomes as compared to their peers, including pre-eclampsia/eclampsia, maternal death, preterm birth, spontaneous abortion, and induced abortion. Additionally, length of stay and total charges for hospitalization are increased. |Adolescent [MESH] |Female [MESH] |Health Care Costs/statistics & numerical data [MESH] |Humans [MESH] |Length of Stay/statistics & numerical data [MESH] |Lupus Erythematosus, Systemic/*complications/economics [MESH] |Pregnancy [MESH] |Pregnancy Complications/economics/*epidemiology/etiology [MESH] |Pregnancy Outcome/epidemiology [MESH] |Prevalence [MESH] |Risk Factors [MESH]Adverse pregnancy outcomes in adolescents and young women with systemi(epmc).pdf DeepDyve Pubget Overpricing