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2018 ; 4
(ä): 15
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Comparison between optical coherence tomography angiography and fluorescein
angiography findings in retinal vasculitis
#MMPMID29692926
Abucham-Neto JZ
; Torricelli AAM
; Lui ACF
; Guimarães SN
; Nascimento H
; Regatieri CV
Int J Retina Vitreous
2018[]; 4
(ä): 15
PMID29692926
show ga
BACKGROUND: To describe optical coherence tomography angiography (OCT-A) findings
in patients with retinal vasculitis and to compare them to current fluorescein
angiography (FA) findings. METHODS: This was an observational case series.
Nineteen eyes in 10 patients with retinal vasculitis of various etiologies were
imaged with FA (TRC-50DX, Topcon) and OCT-A (SD-OCT, Optovue). The images were
reviewed and analyzed. RESULTS: The mean age was 36 years (range 24-67 years);
there were three males and seven females. The primary vessels involved were veins
(89%). Fourteen eyes (74%) had active inflammatory disease during the study
period, with signs of vascular sheathing and perivascular leakage on FA.
Interestingly, in this group, OCT-A was not able to detect clear signs of active
inflammation around the affected vessels. Nevertheless, OCT-A was able to detect
secondary lesions in fourteen eyes (74%), including some findings not clearly
shown on FA. Most of these were within the macular area. OCT-A was particularly
effective in cases of capillary dropout, increased foveal avascular zone,
telangiectasias, shunts, and areas of neovascularization. CONCLUSION: FA remains
an essential complementary exam for detection of retinal vasculitis. However,
OCT-A extends FA findings and affords better assessment of secondary
complications.