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10.2147/CLEP.S156997 http://scihub22266oqcxt.onion/10.2147/CLEP.S156997 C5901199!5901199 !29692631     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29692631 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Epidemiol 2018 ; 10 (ä): 391-399 Nephropedia Template TP {{tp|p=29692631 |t=2018. Pediatric acquired demyelinating syndromes: a nationwide validation study of the Danish National Patient Register |pdf=|usr=}}{{29692631 }} gab.com Text Pediatric acquired demyelinating syndromes: a nationwide validation study of the Danish National Patient Register JO: Clin Epidemiol http://www.kidney.de/pget.php?&tw=1&pmid=29692631 #FOAvip OBJECTIVE: To validate the Danish National Patient Register's (NPR) diagnoses of pediatric acquired demyelinating syndromes (ADS) including multiple sclerosis (MS). STUDY DESIGN AND SETTING: We identified ADS diagnostic groups using International Classification of Diseases (ICD) codes and reviewed medical records to validate the NPR diagnoses during 2008-2015. RESULTS: Among 409 children in the study, 184 children had a validated and final ADS diagnosis after reviewing medical records as follows: optic neuritis (ON; n=46), transverse myelitis (TM; n=16), acute disseminated encephalomyelitis (ADEM; n=50), clinically isolated syndrome (CIS) including dissemination in space (CIS [DIS]) but not dissemination in time (n=6), neuromyelitis optica spectrum disorder (NMOsd; n=5), and MS (n=61). During the mean follow-up of 4.6 years, 33% of children initially diagnosed with monophasic ADS progressed to MS. Positive predictive value (PPV) was 0.71 (95% confidence interval [CI] =0.62-0.80) for ON, 0.64 (95% CI =0.43-0.82) for TM, 0.93 (95% CI =0.84-0.98) for MS, 0.27 (95% CI =0.19-0.35) for CIS, 0.43 (95% CI =0.10-0.82) for NMOsd, and 0.15 (95% CI =0.10-0.20) for ADEM. Assuming complete coverage for non-MS ADS, the sensitivity was 0.99 (95% CI =0.93-1.00) for ON, 0.83 (95% CI =0.36-1.00) for CIS (DIS), and 0.80 (95% CI =0.56-0.94) for TM, but only 0.58 (95% CI =0.43-0.72) for ADEM and 0.60 (95% CI =0.15-0.95) for NMOsd. CONCLUSION: PPV was high for MS and considered acceptable for ON and TM; therefore, these ICD revision 10 (ICD-10) codes from the NPR are useful for epidemiological studies. Conversely, PPV was low for CIS and ADEM; NMOsd was inconclusive. Twit Text FOAVip Pediatric acquired demyelinating syndromes: a nationwide validation study of the Danish National Patient Register ????Clin Epidemiol http://www.kidney.de/pget.php?&tw=1&pmid=29692631 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29692631 #FOAvip English Wikipedia <ref>{{Cite pmid|29692631 }}</ref> Pediatric acquired demyelinating syndromes: a nationwide validation study of the Danish National Patient Register #MMPMID29692631 Boesen MS ; Magyari M ; Born AP ; Thygesen LC Clin Epidemiol 2018[]; 10 (ä): 391-399 PMID29692631 show ga OBJECTIVE: To validate the Danish National Patient Register's (NPR) diagnoses of pediatric acquired demyelinating syndromes (ADS) including multiple sclerosis (MS). STUDY DESIGN AND SETTING: We identified ADS diagnostic groups using International Classification of Diseases (ICD) codes and reviewed medical records to validate the NPR diagnoses during 2008-2015. RESULTS: Among 409 children in the study, 184 children had a validated and final ADS diagnosis after reviewing medical records as follows: optic neuritis (ON; n=46), transverse myelitis (TM; n=16), acute disseminated encephalomyelitis (ADEM; n=50), clinically isolated syndrome (CIS) including dissemination in space (CIS [DIS]) but not dissemination in time (n=6), neuromyelitis optica spectrum disorder (NMOsd; n=5), and MS (n=61). During the mean follow-up of 4.6 years, 33% of children initially diagnosed with monophasic ADS progressed to MS. Positive predictive value (PPV) was 0.71 (95% confidence interval [CI] =0.62-0.80) for ON, 0.64 (95% CI =0.43-0.82) for TM, 0.93 (95% CI =0.84-0.98) for MS, 0.27 (95% CI =0.19-0.35) for CIS, 0.43 (95% CI =0.10-0.82) for NMOsd, and 0.15 (95% CI =0.10-0.20) for ADEM. Assuming complete coverage for non-MS ADS, the sensitivity was 0.99 (95% CI =0.93-1.00) for ON, 0.83 (95% CI =0.36-1.00) for CIS (DIS), and 0.80 (95% CI =0.56-0.94) for TM, but only 0.58 (95% CI =0.43-0.72) for ADEM and 0.60 (95% CI =0.15-0.95) for NMOsd. CONCLUSION: PPV was high for MS and considered acceptable for ON and TM; therefore, these ICD revision 10 (ICD-10) codes from the NPR are useful for epidemiological studies. Conversely, PPV was low for CIS and ADEM; NMOsd was inconclusive. äPediatric acquired demyelinating syndromes: a nationwide validation st(epmc).pdf DeepDyve Pubget Overpricing