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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Neurosurg+Clin+N+Am 2016 ; 27 (4): 441-52 Nephropedia Template TP
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Concussion - Mild TBI: Recoverable Injury with Potential for Serious Sequelae #MMPMID27637394
Kamins J; Giza CC
Neurosurg Clin N Am 2016[Oct]; 27 (4): 441-52 PMID27637394show ga
Concussion is increasingly recognized as a major public health issue. The majority of patients will return to baseline and experience full recovery, although a subset experience persistent symptoms. Newer animal models and imaging studies are beginning to demonstrate that metabolic and neurovascular resolution may actually take longer than symptomatic recovery. Repeat TBI within the metabolic window of dysfunction may result in worsened symptoms and prolonged recovery. The true risk for second impact syndrome appears to be small, and development of cerebral edema after a mild impact may be related to genetic risks rather than serial impacts. Additionally, there is mounting evidence that exposure to multiple concussions, despite an apparent return to normalcy, may increase risk for remote neurologic syndromes later in life. Subconcussive impacts have been described as head impacts that occur repeatedly and without neurological signs or symptoms, and have been proposed to contribute to delayed or progressive neurological deficits.