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2018 ; 18
(1
): 99
Nephropedia Template TP
gab.com Text
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A systematic review of non-antibiotic measures for the prevention of urinary
tract infections in pregnancy
#MMPMID29653573
Ghouri F
; Hollywood A
; Ryan K
BMC Pregnancy Childbirth
2018[Apr]; 18
(1
): 99
PMID29653573
show ga
BACKGROUND: Urinary tract infections (UTIs) are common in pregnancy and account
for the highest proportion of primary care antibiotic prescriptions issued to
pregnant women in the UK. It is well known that antibiotic use is associated with
increased antimicrobial resistance and therefore measures to minimise antibiotic
use for UTI prevention have been studied. The efficacy and safety of these
measures in pregnancy have not been addressed and therefore the aim of this study
was to systematically review the literature to identify and evaluate potential
measures to prevent UTIs in pregnant women. METHODS: Ten databases (EMBASE, AMED,
BNI, CINAHL, Medline, PubMed, PsycINFO, Cochrane Trials, Scopus and Science
Direct) were systematically searched in July 2017 for studies reporting
non-antibiotic measures to prevent UTIs in pregnancy. The terms ("urinary tract
infection" or UTI or bacteriuria or cystitis) AND (prevention) AND (pregnan*)
were used. The quality of the publications was appraised using the Critical
Appraisal Skills Programme (CASP) checklists for cohort study, case-control study
and randomised controlled trial. The results were synthesised using a textual
narrative approach. RESULTS: Search results yielded 3276 publications and after
reviewing titles and removing duplicates, 57 full text articles were assessed for
eligibility and eight were included in the review. Five different approaches
(hygiene measures, cranberry juice, immunisation, ascorbic acid and CanephronŽ N)
have been identified, all of which are reported to be safe in pregnancy.
CONCLUSION: The quality of the evidence varied considerably and only hygiene
measures were supported by evidence to be recommended in practice. Future work
needs to concentrate on strengthening the evidence base through improved design
and reporting of studies with a focus on immunisation, ascorbic acid and
CanephronŽ N.
|Ascorbic Acid/therapeutic use
[MESH]
|Dietary Supplements
[MESH]
|Female
[MESH]
|Fruit and Vegetable Juices
[MESH]
|Humans
[MESH]
|Hygiene
[MESH]
|Immunization/methods
[MESH]
|Phytotherapy/methods
[MESH]
|Plant Extracts/therapeutic use
[MESH]
|Pregnancy
[MESH]
|Pregnancy Complications, Infectious/*prevention & control
[MESH]
|Prenatal Care/*methods
[MESH]
|Urinary Tract Infections/*prevention & control
[MESH]
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