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10.1038/s41467-018-03705-y http://scihub22266oqcxt.onion/10.1038/s41467-018-03705-y C5897557!5897557!29650952     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=29650952|t=2018. Progress and challenges towards targeted delivery of cancer therapeutics |pdf=|usr=}}{{29650952}} gab.com Text Progress and challenges towards targeted delivery of cancer therapeutics JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=29650952 #FOAvip Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past few decades. However, compared to the plethora of successful pre-clinical studies, only 15 passively targeted nanocarriers (NCs) have been approved for clinical use and none of the actively targeted NCs have advanced past clinical trials. Herein, we review the principles behind targeted delivery approaches to determine potential reasons for their limited clinical translation and success. We propose criteria and considerations that must be taken into account for the development of novel actively targeted NCs. We also highlight the possible directions for the development of successful tumor targeting strategies. Twit Text FOAVip Progress and challenges towards targeted delivery of cancer therapeutics ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=29650952 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29650952 #FOAvip English Wikipedia <ref>{{Cite pmid|29650952}}</ref> Progress and challenges towards targeted delivery of cancer therapeutics #MMPMID29650952 Rosenblum D; Joshi N; Tao W; Karp JM; Peer D Nat Commun 2018[]; 9 (ä): ä PMID29650952show ga Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past few decades. However, compared to the plethora of successful pre-clinical studies, only 15 passively targeted nanocarriers (NCs) have been approved for clinical use and none of the actively targeted NCs have advanced past clinical trials. Herein, we review the principles behind targeted delivery approaches to determine potential reasons for their limited clinical translation and success. We propose criteria and considerations that must be taken into account for the development of novel actively targeted NCs. We also highlight the possible directions for the development of successful tumor targeting strategies. äProgress and challenges towards targeted delivery of cancer therapeuti(epmc).pdf DeepDyve Pubget Overpricing