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10.1155/2018/9451950

http://scihub22266oqcxt.onion/10.1155/2018/9451950
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C5896258!5896258!29785172
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suck abstract from ncbi


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pmid29785172      Mediators+Inflamm 2018 ; 2018 (ä): ä
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  • Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular Senescence #MMPMID29785172
  • Kuba A; Raida L
  • Mediators Inflamm 2018[]; 2018 (ä): ä PMID29785172show ga
  • Graft versus host disease (GVHD), a severe immunogenic complication of allogeneic hematopoietic stem cell transplantation (HSCT), represents the most frequent cause of transplant-related mortality (TRM). Despite a huge progress in HSCT techniques and posttransplant care, GVHD remains a significant obstacle in successful HSCT outcome. This review presents a complex summary of GVHD pathogenesis with focus on references considering basic biological processes such as DNA damage response and cellular senescence.
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