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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biostat+Biom+Open+Access+J 2018 ; 5 (3): ä Nephropedia Template TP
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Statistical Methods for Clinical Trial Designs in the New Era of Cancer Treatment #MMPMID29645007
Guo B; Zhang R
Biostat Biom Open Access J 2018[Feb]; 5 (3): ä PMID29645007show ga
Recent success of immunotherapy and other targeted therapies in cancer treatment has signaled the advent of precision medicine. Unlike conventional trial designs that aim to find an optimal treatment ignoring inter-patient heterogeneity, clinical trial designs for precision medicine must take into account patients? variability in genes, environments, and lifestyle. This article provides a review of recent research development of clinical trial designs toward this trend.