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10.1073/pnas.1801912115

http://scihub22266oqcxt.onion/10.1073/pnas.1801912115
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suck abstract from ncbi


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pmid29559529      Proc+Natl+Acad+Sci+U+S+A 2018 ; 115 (14): 3710-5
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  • Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism #MMPMID29559529
  • Avino TA; Barger N; Vargas MV; Carlson EL; Amaral DG; Bauman MD; Schumann CM
  • Proc Natl Acad Sci U S A 2018[Apr]; 115 (14): 3710-5 PMID29559529show ga
  • We demonstrate that the number of mature neurons in the human amygdala increases from childhood into adulthood. This trajectory may be due to the incorporation of immature neurons from the paralaminar nucleus in the ventral amygdala. In contrast, individuals with autism spectrum disorder (ASD) show an initial excess of mature neurons followed by a decline into adulthood. Our results suggest a degenerative component in ASD and highlight the need for a more comprehensive understanding of the protracted cellular development of the human amygdala for multiple psychiatric disorders.
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