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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Lancet+Neurol
2018 ; 17
(4
): 347-361
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English Wikipedia
Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory,
cardiac, bone health, and orthopaedic management
#MMPMID29395990
Birnkrant DJ
; Bushby K
; Bann CM
; Alman BA
; Apkon SD
; Blackwell A
; Case LE
; Cripe L
; Hadjiyannakis S
; Olson AK
; Sheehan DW
; Bolen J
; Weber DR
; Ward LM
Lancet Neurol
2018[Apr]; 17
(4
): 347-361
PMID29395990
show ga
A coordinated, multidisciplinary approach to care is essential for optimum
management of the primary manifestations and secondary complications of Duchenne
muscular dystrophy (DMD). Contemporary care has been shaped by the availability
of more sensitive diagnostic techniques and the earlier use of therapeutic
interventions, which have the potential to improve patients' duration and quality
of life. In part 2 of this update of the DMD care considerations, we present the
latest recommendations for respiratory, cardiac, bone health and osteoporosis,
and orthopaedic and surgical management for boys and men with DMD. Additionally,
we provide guidance on cardiac management for female carriers of a
disease-causing mutation. The new care considerations acknowledge the effects of
long-term glucocorticoid use on the natural history of DMD, and the need for care
guidance across the lifespan as patients live longer. The management of DMD looks
set to change substantially as new genetic and molecular therapies become
available.