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2018 ; 2018
(3
): rjy055
Nephropedia Template TP
gab.com Text
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English Wikipedia
A case of Dupuytren s disease managed with viable cryopreserved placental
membrane adjunct to open palmar fasciectomy
#MMPMID29644033
Dress CM
; Tassis EK
J Surg Case Rep
2018[Mar]; 2018
(3
): rjy055
PMID29644033
show ga
Dupuytren's disease (DD) is a rare connective tissue disorder resulting in
progressive fibrosis and thickening of the palmar fascia, and contracture of the
fingers due to excessive collagen deposition. Staged surgical interventions are
reserved for severe cases, yet worsening of fibrosis and contracture of fingers
post-surgery, has been reported to have a recurrence rate as high as 85%. Here,
the authors report on use of viable cryopreserved placental membrane (vCPM)
allograft as an adjunct to open fasciectomy. In a patient with debilitating
bilateral DD contractures of >20 years duration, this novel approach resulted in
a 34.8% range of motion (ROM) improvement and ability to fully extend all digits
of the right hand. No adverse events were recorded. At 1 year post-surgery, the
patient has no decrease in ROM. Results indicate that vCPM incorporation in open
fasciectomy may provide benefit in reducing contracture recurrence in DD
patients.