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2018 ; 7
(1
): 114-120
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gab.com Text
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English Wikipedia
A case of ABO-incompatible blood transfusion treated by plasma exchange therapy
and continuous hemodiafiltration
#MMPMID29383577
Namikawa A
; Shibuya Y
; Ouchi H
; Takahashi H
; Furuto Y
CEN Case Rep
2018[May]; 7
(1
): 114-120
PMID29383577
show ga
ABO-incompatible blood transfusion is potentially a life-threatening event. A
74-year-old type O Rh-positive male was accidentally transfused with 280 mL type
B Rh-positive red blood cells during open right hemicolectomy, causing
ABO-incompatible blood transfusion. Immediately after the transfusion, the
patient experienced a hypotension episode followed by acute hemolytic reaction,
disseminated intravascular coagulation and acute kidney injury. Plasma exchange
therapy was performed to remove anti-B antibody and free hemoglobin because they
caused acute hemolytic reaction, disseminated intravascular coagulation, and
acute kidney injury. Free hemoglobin levels decreased from 13 to 2 mg/dL for 2 h.
Continuous hemodiafiltration was used to stabilize hemodynamics. The patient was
successfully treated for acute hemolytic reaction, disseminated intravascular
coagulation, and acute kidney injury. Plasma exchange therapy and continuous
hemodiafiltration are likely to be effective treatments for ABO-incompatible
blood transfusion, and further studies are required to assess this effectiveness
in future.