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10.1093/hmg/ddx306 http://scihub22266oqcxt.onion/10.1093/hmg/ddx306 C5886466!5886466!28977451     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Hum+Mol+Genet 2017 ; 26 (R2): R208-15 Nephropedia Template TP {{tp|p=28977451|t=2017. Between form and function: the complexity of genome folding |pdf=|usr=}}{{28977451}} gab.com Text Between form and function: the complexity of genome folding JO: Hum Mol Genet http://www.kidney.de/pget.php?&tw=1&pmid=28977451 #FOAvip It has been known for over a century that chromatin is not randomly distributed within the nucleus. However, the question of how DNA is folded and the influence of such folding on nuclear processes remain topics of intensive current research. A longstanding, unanswered question is whether nuclear organization is simply a reflection of nuclear processes such as transcription and replication, or whether chromatin is folded by independent mechanisms and this per se encodes function? Evidence is emerging that both may be true. Here, using the ?-globin gene cluster as an illustrative model, we provide an overview of the most recent insights into the layers of genome organization across different scales and how this relates to gene activity. Twit Text FOAVip Between form and function: the complexity of genome folding ????Hum Mol Genet http://www.kidney.de/pget.php?&tw=1&pmid=28977451 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28977451 #FOAvip English Wikipedia <ref>{{Cite pmid|28977451}}</ref> Between form and function: the complexity of genome folding #MMPMID28977451 Oudelaar AM; Hanssen LL; Hardison RC; Kassouf MT; Hughes JR; Higgs DR Hum Mol Genet 2017[Oct]; 26 (R2): R208-15 PMID28977451show ga It has been known for over a century that chromatin is not randomly distributed within the nucleus. However, the question of how DNA is folded and the influence of such folding on nuclear processes remain topics of intensive current research. A longstanding, unanswered question is whether nuclear organization is simply a reflection of nuclear processes such as transcription and replication, or whether chromatin is folded by independent mechanisms and this per se encodes function? Evidence is emerging that both may be true. Here, using the ?-globin gene cluster as an illustrative model, we provide an overview of the most recent insights into the layers of genome organization across different scales and how this relates to gene activity. äBetween form and function: the complexity of genome folding (epmc).pdf DeepDyve Pubget Overpricing