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10.1016/j.cub.2016.05.036 http://scihub22266oqcxt.onion/10.1016/j.cub.2016.05.036 C5884674!5884674!27345163     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Biol 2016 ; 26 (14): 1829-42 Nephropedia Template TP {{tp|p=27345163|t=2016. Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis |pdf=|usr=}}{{27345163}} gab.com Text Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis JO: Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=27345163 #FOAvip Epithelial integrity and barrier function must be maintained during the complex cell shape changes that occur during cytokinesis in vertebrate epithelial tissue. Here, we investigate how adherens junctions and bicellular and tricellular tight junctions are maintained and remodeled during cell division in the Xenopus laevis embryo. We find that epithelial barrier function is not disrupted during cytokinesis and is mediated by sustained tight junctions. Using FRAP, we demonstrate that adherens junction proteins are stabilized at the cleavage furrow by increased tension. We find that vinculin is recruited to the adherens junction at the cleavage furrow, and inhibiting recruitment of vinculin by expressing a dominant negative mutant increases the rate of furrow ingression. Furthermore, we show that cells neighboring the cleavage plane are pulled between the daughter cells, making a new interface between neighbors, and two new tricellular tight junctions flank the midbody following cytokinesis. Our data provide new insight into how epithelial integrity and barrier function are maintained throughout cytokinesis in vertebrate epithelial tissue. Twit Text FOAVip Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis ????Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=27345163 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27345163 #FOAvip English Wikipedia <ref>{{Cite pmid|27345163}}</ref> Maintenance of the epithelial barrier and remodeling of cell-cell junctions during cytokinesis #MMPMID27345163 Higashi T; Arnold TR; Stephenson RE; Dinshaw KM; Miller AL Curr Biol 2016[Jul]; 26 (14): 1829-42 PMID27345163show ga Epithelial integrity and barrier function must be maintained during the complex cell shape changes that occur during cytokinesis in vertebrate epithelial tissue. Here, we investigate how adherens junctions and bicellular and tricellular tight junctions are maintained and remodeled during cell division in the Xenopus laevis embryo. We find that epithelial barrier function is not disrupted during cytokinesis and is mediated by sustained tight junctions. Using FRAP, we demonstrate that adherens junction proteins are stabilized at the cleavage furrow by increased tension. We find that vinculin is recruited to the adherens junction at the cleavage furrow, and inhibiting recruitment of vinculin by expressing a dominant negative mutant increases the rate of furrow ingression. Furthermore, we show that cells neighboring the cleavage plane are pulled between the daughter cells, making a new interface between neighbors, and two new tricellular tight junctions flank the midbody following cytokinesis. Our data provide new insight into how epithelial integrity and barrier function are maintained throughout cytokinesis in vertebrate epithelial tissue. äMaintenance of the epithelial barrier and remodeling of cell-cell junc(epmc).pdf DeepDyve Pubget Overpricing