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10.1016/j.tranon.2018.01.019 http://scihub22266oqcxt.onion/10.1016/j.tranon.2018.01.019 C5884214!5884214!29425952     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transl+Oncol 2018 ; 11 (2): 330-7 Nephropedia Template TP {{tp|p=29425952|t=2018. Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs |pdf=|usr=}}{{29425952}} gab.com Text Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs JO: Transl Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29425952 #FOAvip William Coley, between 1895 and 1936, treated hundreds of cancer patients using infusions of fever inducing bacerial extracts. Similar experiments were done by Klyuyeva and co-workers in the 1940ies in Russia using trypanosoma extracts. Many remissions and cures were reported. We have conjectured that pathogen associated molecular pattern substances (PAMP) are the molecular explanation for the beneficial treatments in both groups. We could show that a combination of PAMP can eradicate solid tumours in cancer mice if applied several times. Accordingly, we suggested to combine PAMP containing approved drugs to treat cancer patients using a protocol similar to the old fever induction regimen. In this retrospective phase-1 study we report on the fever induction capacity and safety of applications of bacterial extracts, combinations of bacterial extracts with approved drugs, and combinations of approved drugs in 131 mainly cancer patients. Adverse reactions were those which can be expected during a feverish infection and mild. Over 523 fever inductions, no severe adverse reaction was observed. Twit Text FOAVip Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs ????Transl Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29425952 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29425952 #FOAvip English Wikipedia <ref>{{Cite pmid|29425952}}</ref> Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs #MMPMID29425952 Reuter URM; Oettmeier R; Hobohm U Transl Oncol 2018[Apr]; 11 (2): 330-7 PMID29425952show ga William Coley, between 1895 and 1936, treated hundreds of cancer patients using infusions of fever inducing bacerial extracts. Similar experiments were done by Klyuyeva and co-workers in the 1940ies in Russia using trypanosoma extracts. Many remissions and cures were reported. We have conjectured that pathogen associated molecular pattern substances (PAMP) are the molecular explanation for the beneficial treatments in both groups. We could show that a combination of PAMP can eradicate solid tumours in cancer mice if applied several times. Accordingly, we suggested to combine PAMP containing approved drugs to treat cancer patients using a protocol similar to the old fever induction regimen. In this retrospective phase-1 study we report on the fever induction capacity and safety of applications of bacterial extracts, combinations of bacterial extracts with approved drugs, and combinations of approved drugs in 131 mainly cancer patients. Adverse reactions were those which can be expected during a feverish infection and mild. Over 523 fever inductions, no severe adverse reaction was observed. äSafety of Therapeutic Fever Induction in Cancer Patients Using Approve(epmc).pdf DeepDyve Pubget Overpricing