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10.3389/fimmu.2018.00635 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.00635 C5882789!5882789 !29643856     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29643856 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Front+Immunol 2018 ; 9 (ä): 635 Nephropedia Template TP {{tp|p=29643856 |t=2018. The Contribution of Non-Professional Antigen-Presenting Cells to Immunity and Tolerance in the Liver |pdf=|usr=}}{{29643856 }} gab.com Text The Contribution of Non-Professional Antigen-Presenting Cells to Immunity and Tolerance in the Liver JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29643856 #FOAvip The liver represents a unique organ biased toward a tolerogenic milieu. Due to its anatomical location, it is constantly exposed to microbial and food-derived antigens from the gut and thus equipped with a complex cellular network that ensures dampening T-cell responses. Within this cellular network, parenchymal cells (hepatocytes), non-parenchymal cells (liver sinusoidal endothelial cells and hepatic stellate cells), and immune cells contribute directly or indirectly to this process. Despite this refractory bias, the liver is capable of mounting efficient T-cell responses. How the various antigen-presenting cell (APC) populations contribute to this process and how they handle danger signals determine the outcome of the generated immune responses. Importantly, liver mounted responses convey consequences not only for the local but also to systemic immunity. Here, we discuss various aspects of antigen presentation and its consequences by the non-professional APCs in the liver microenvironment. Twit Text FOAVip The Contribution of Non-Professional Antigen-Presenting Cells to Immunity and Tolerance in the Liver ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29643856 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29643856 #FOAvip English Wikipedia <ref>{{Cite pmid|29643856 }}</ref> The Contribution of Non-Professional Antigen-Presenting Cells to Immunity and Tolerance in the Liver #MMPMID29643856 Mehrfeld C ; Zenner S ; Kornek M ; Lukacs-Kornek V Front Immunol 2018[]; 9 (ä): 635 PMID29643856 show ga The liver represents a unique organ biased toward a tolerogenic milieu. Due to its anatomical location, it is constantly exposed to microbial and food-derived antigens from the gut and thus equipped with a complex cellular network that ensures dampening T-cell responses. Within this cellular network, parenchymal cells (hepatocytes), non-parenchymal cells (liver sinusoidal endothelial cells and hepatic stellate cells), and immune cells contribute directly or indirectly to this process. Despite this refractory bias, the liver is capable of mounting efficient T-cell responses. How the various antigen-presenting cell (APC) populations contribute to this process and how they handle danger signals determine the outcome of the generated immune responses. Importantly, liver mounted responses convey consequences not only for the local but also to systemic immunity. Here, we discuss various aspects of antigen presentation and its consequences by the non-professional APCs in the liver microenvironment. |Animals [MESH] |Antigen Presentation [MESH] |Antigen-Presenting Cells/*immunology [MESH] |Endothelial Cells/*immunology [MESH] |Hepatic Stellate Cells/*immunology [MESH] |Hepatocytes/*immunology [MESH] |Homeostasis [MESH] |Humans [MESH] |Immune Tolerance [MESH] |Immunity, Cellular [MESH] |Liver/*immunology [MESH]The Contribution of Non-Professional Antigen-Presenting Cells to Immun(epmc).pdf DeepDyve Pubget Overpricing