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10.5483/BMBRep.2018.51.3.012 http://scihub22266oqcxt.onion/10.5483/BMBRep.2018.51.3.012 C5882222!5882222!29353600     free     free     free       BMB+Rep 2018 ; 51 (3): 151-6 Nephropedia Template TP {{tp|p=29353600|t=2018. Regulation of Hippo signaling by actin remodeling |pdf=|usr=}}{{29353600}} gab.com Text Regulation of Hippo signaling by actin remodeling JO: BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip The Hippo signaling pathway controls nuclear accumulation and stability of the transcriptional coregulator YAP and its paralog TAZ. The activity of Hippo-YAP signaling is influenced not only by biochemical signals, but also by cell shape and mechanical tension transmitted through cell-cell junctions and cell-matrix adhesions. Data accumulated thus far indicates that the actin cytoskeleton is a key mediator of the regulation of Hippo-YAP signaling by means of a variety of biochemical and mechanical cues. In this review, we have outlined the role of actin dynamics and actin-associated proteins in the regulation of Hippo-YAP signaling. In addition, we discuss actin-mediated regulation of YAP/TAZ activity independent of the core Hippo kinases MST and LATS. Although our understanding of the link between Hippo-YAP signaling and the actin cytoskeleton is progressing rapidly, many open questions remain. Twit Text FOAVip Regulation of Hippo signaling by actin remodeling ????BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip English Wikipedia <ref>{{Cite pmid|29353600}}</ref> Regulation of Hippo signaling by actin remodeling #MMPMID29353600 Seo J; Kim J BMB Rep 2018[Mar]; 51 (3): 151-6 PMID29353600show ga The Hippo signaling pathway controls nuclear accumulation and stability of the transcriptional coregulator YAP and its paralog TAZ. The activity of Hippo-YAP signaling is influenced not only by biochemical signals, but also by cell shape and mechanical tension transmitted through cell-cell junctions and cell-matrix adhesions. Data accumulated thus far indicates that the actin cytoskeleton is a key mediator of the regulation of Hippo-YAP signaling by means of a variety of biochemical and mechanical cues. In this review, we have outlined the role of actin dynamics and actin-associated proteins in the regulation of Hippo-YAP signaling. In addition, we discuss actin-mediated regulation of YAP/TAZ activity independent of the core Hippo kinases MST and LATS. Although our understanding of the link between Hippo-YAP signaling and the actin cytoskeleton is progressing rapidly, many open questions remain. äRegulation of Hippo signaling by actin remodeling (epmc).pdf DeepDyve Pubget Overpricing