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10.1186/s40780-018-0101-7

http://scihub22266oqcxt.onion/10.1186/s40780-018-0101-7
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suck abstract from ncbi


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pmid29619240      J+Pharm+Health+Care+Sci 2018 ; 4 (ä): ä
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  • Comparison of PETINIA and LC-MS/MS for determining plasma mycophenolic acid concentrations in Japanese lung transplant recipients #MMPMID29619240
  • Kikuchi M; Tanaka M; Takasaki S; Takahashi A; Akiba M; Matsuda Y; Noda M; Hisamichi K; Yamaguchi H; Okada Y; Mano N
  • J Pharm Health Care Sci 2018[]; 4 (ä): ä PMID29619240show ga
  • Background: Mycophenolic acid (MPA) treatment requires therapeutic drug monitoring to improve the outcome after organ transplantation. The aim of this study was to compare two methods, a particle enhanced turbidimetric inhibition immunoassay (PETINIA) and a reference liquid chromatography tandem mass spectrometry (LC-MS/MS) for determining plasma MPA concentrations from Japanese lung transplant recipients. Methods: Plasma MPA concentrations were determined from 20 Japanese lung transplant recipients using LC-MS/MS and the PETINIA on the Dimension Xpand Plus-HM analyzer. Results: The mean MPA concentration measured by PETINIA was significantly higher than that measured by LC-MS/MS (3.26?±?2.73 ?g/mL versus 2.82?±?2.71 ?g/mL, P?
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