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10.1073/pnas.1718304115 http://scihub22266oqcxt.onion/10.1073/pnas.1718304115 C5879681!5879681!29507209     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2018 ; 115 (13): E2980-7 Nephropedia Template TP {{tp|p=29507209|t=2018. Linking imaging to omics utilizing image-guided tissue extraction |pdf=|usr=}}{{29507209}} gab.com Text Linking imaging to omics utilizing image-guided tissue extraction JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=29507209 #FOAvip Imaging provides an insight into biological patho-mechanisms of diseases. However, the link between the imaging phenotype and the underlying molecular processes is often not well understood. Methods such as metabolomics and proteomics reveal detailed information about these processes. Unfortunately, they provide no spatial information and thus cannot be easily correlated with functional imaging. We have developed an image-guided milling machine and unique workflows to precisely isolate tissue samples based on imaging data. The tissue samples remain cooled during the entire procedure, preventing sample degradation. This enables us to correlate, at an unprecedented spatial precision, comprehensive imaging information with metabolomics and proteomics data, leading to a better understanding of diseases. Twit Text FOAVip Linking imaging to omics utilizing image-guided tissue extraction ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=29507209 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29507209 #FOAvip English Wikipedia <ref>{{Cite pmid|29507209}}</ref> Linking imaging to omics utilizing image-guided tissue extraction #MMPMID29507209 Disselhorst JA; Krueger MA; Ud-Dean SMM; Bezrukov I; Jarboui MA; Trautwein C; Traube A; Spindler C; Cotton JM; Leibfritz D; Pichler BJ Proc Natl Acad Sci U S A 2018[Mar]; 115 (13): E2980-7 PMID29507209show ga Imaging provides an insight into biological patho-mechanisms of diseases. However, the link between the imaging phenotype and the underlying molecular processes is often not well understood. Methods such as metabolomics and proteomics reveal detailed information about these processes. Unfortunately, they provide no spatial information and thus cannot be easily correlated with functional imaging. We have developed an image-guided milling machine and unique workflows to precisely isolate tissue samples based on imaging data. The tissue samples remain cooled during the entire procedure, preventing sample degradation. This enables us to correlate, at an unprecedented spatial precision, comprehensive imaging information with metabolomics and proteomics data, leading to a better understanding of diseases. äLinking imaging to omics utilizing image-guided tissue extraction (epmc).pdf DeepDyve Pubget Overpricing