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10.3390/ijms19030905

http://scihub22266oqcxt.onion/10.3390/ijms19030905
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C5877766!5877766!29562695
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suck abstract from ncbi


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pmid29562695      Int+J+Mol+Sci 2018 ; 19 (3): ä
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  • Galectins as Molecular Targets for Therapeutic Intervention #MMPMID29562695
  • Dings RPM; Miller MC; Griffin RJ; Mayo KH
  • Int J Mol Sci 2018[Mar]; 19 (3): ä PMID29562695show ga
  • Galectins are a family of small, highly conserved, molecular effectors that mediate various biological processes, including chemotaxis and angiogenesis, and that function by interacting with various cell surface glycoconjugates, usually targeting ?-galactoside epitopes. Because of their significant involvement in various biological functions and pathologies, galectins have become a focus of therapeutic discovery for clinical intervention against cancer, among other pathological disorders. In this review, we focus on understanding galectin structure-function relationships, their mechanisms of action on the molecular level, and targeting them for therapeutic intervention against cancer.
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