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10.3390/ijms19030664 http://scihub22266oqcxt.onion/10.3390/ijms19030664 C5877525!5877525 !29495444     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29495444 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2018 ; 19 (3 ): ä Nephropedia Template TP {{tp|p=29495444 |t=2018. Magnesium Replacement to Protect Cardiovascular and Kidney Damage? Lack of Prospective Clinical Trials |pdf=|usr=}}{{29495444 }} gab.com Text Magnesium Replacement to Protect Cardiovascular and Kidney Damage Lack of Prospective Clinical Trials JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29495444 #FOAvip Patients with advanced chronic kidney disease exhibit an increase in cardiovascular mortality. Recent works have shown that low levels of magnesium are associated with increased cardiovascular and all-cause mortality in hemodialysis patients. Epidemiological studies suggest an influence of low levels of magnesium on the occurrence of cardiovascular disease, which is also observed in the normal population. Magnesium is involved in critical cellular events such as apoptosis and oxidative stress. It also participates in a number of enzymatic reactions. In animal models of uremia, dietary supplementation of magnesium reduces vascular calcifications and mortality; in vitro, an increase of magnesium concentration decreases osteogenic transdifferentiation of vascular smooth muscle cells. Therefore, it may be appropriate to evaluate whether magnesium replacement should be administered in an attempt to reduce vascular damage and mortality in the uremic population In the present manuscript, we will review the magnesium homeostasis, the involvement of magnesium in enzymatic reactions, apoptosis and oxidative stress and the clinical association between magnesium and cardiovascular disease in the general population and in the context of chronic kidney disease. We will also analyze the role of magnesium on kidney function. Finally, the experimental evidence of the beneficial effects of magnesium replacement in chronic kidney disease will be thoroughly described. Twit Text FOAVip Magnesium Replacement to Protect Cardiovascular and Kidney Damage Lack of Prospective Clinical Trials ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29495444 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29495444 #FOAvip English Wikipedia <ref>{{Cite pmid|29495444 }}</ref> Magnesium Replacement to Protect Cardiovascular and Kidney Damage? Lack of Prospective Clinical Trials #MMPMID29495444 Muñoz-Castañeda JR ; Pendón-Ruiz de Mier MV ; Rodríguez M ; Rodríguez-Ortiz ME Int J Mol Sci 2018[Feb]; 19 (3 ): ä PMID29495444 show ga Patients with advanced chronic kidney disease exhibit an increase in cardiovascular mortality. Recent works have shown that low levels of magnesium are associated with increased cardiovascular and all-cause mortality in hemodialysis patients. Epidemiological studies suggest an influence of low levels of magnesium on the occurrence of cardiovascular disease, which is also observed in the normal population. Magnesium is involved in critical cellular events such as apoptosis and oxidative stress. It also participates in a number of enzymatic reactions. In animal models of uremia, dietary supplementation of magnesium reduces vascular calcifications and mortality; in vitro, an increase of magnesium concentration decreases osteogenic transdifferentiation of vascular smooth muscle cells. Therefore, it may be appropriate to evaluate whether magnesium replacement should be administered in an attempt to reduce vascular damage and mortality in the uremic population In the present manuscript, we will review the magnesium homeostasis, the involvement of magnesium in enzymatic reactions, apoptosis and oxidative stress and the clinical association between magnesium and cardiovascular disease in the general population and in the context of chronic kidney disease. We will also analyze the role of magnesium on kidney function. Finally, the experimental evidence of the beneficial effects of magnesium replacement in chronic kidney disease will be thoroughly described. |Animals [MESH] |Apoptosis/drug effects [MESH] |Cardiovascular Diseases/etiology/metabolism/pathology/prevention & control [MESH] |Cardiovascular System/drug effects/*metabolism [MESH] |Disease Progression [MESH] |Drug Overdose [MESH] |Enzyme Activation/drug effects [MESH] |Humans [MESH] |Kidney/drug effects/*metabolism [MESH] |Magnesium/blood/*metabolism/pharmacology/therapeutic use [MESH] |Oxidative Stress/drug effects [MESH] |Protective Agents/metabolism/pharmacology [MESH]Magnesium Replacement to Protect Cardiovascular and Kidney Damage? Lac(epmc).pdf DeepDyve Pubget Overpricing