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10.1038/s41598-018-23604-y http://scihub22266oqcxt.onion/10.1038/s41598-018-23604-y C5876400!5876400 !29599467     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29599467 &cmd=llinks): Failed to open stream: HTTP request failed! 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Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus |pdf=|usr=}}{{29599467 }} gab.com Text Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29599467 #FOAvip Diabetic Retinopathy (DR) is an extremely severe and common degenerative disease. The purpose of this study was to quantify the relationship between various parameters including the Foveal Avascular Zone (FAZ) morphology, retinal layer thickness, and retinal hemodynamic properties in healthy controls and patients with diabetes mellitus (DM) with and with no mild DR (MDR) using Spectral-Domain Optical Coherence Tomography (Spectralis SDOCT, Heidelberg Engineering GmbH, Germany) and the Retinal Function Imager (Optical Imaging, Ltd., Rehovot, Israel). Our results showed a higher FAZ area and diameter in MDR patients. Blood flow analysis also showed that there is a significantly smaller venous blood flow velocity in MDR patients. Also, a significant difference in roundness was observed between DM and MDR groups supporting the development of asymmetrical FAZ expansion with worsening DR. Our results suggest a potential anisotropy in the mechanical properties of the diabetic retina with no retinopathy that may trigger the FAZ elongation in a preferred direction resulting in either thinning or thickening of intraretinal layers in the inner and outer segments of the retina as a result of autoregulation. A detailed understanding of these relationships may facilitate earlier detection of DR, allowing for preservation of vision and better clinical outcomes. Twit Text FOAVip Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29599467 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29599467 #FOAvip English Wikipedia <ref>{{Cite pmid|29599467 }}</ref> Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus #MMPMID29599467 Bates NM ; Tian J ; Smiddy WE ; Lee WH ; Somfai GM ; Feuer WJ ; Shiffman JC ; Kuriyan AE ; Gregori NZ ; Kostic M ; Pineda S ; Cabrera DeBuc D Sci Rep 2018[Mar]; 8 (1 ): 5355 PMID29599467 show ga Diabetic Retinopathy (DR) is an extremely severe and common degenerative disease. The purpose of this study was to quantify the relationship between various parameters including the Foveal Avascular Zone (FAZ) morphology, retinal layer thickness, and retinal hemodynamic properties in healthy controls and patients with diabetes mellitus (DM) with and with no mild DR (MDR) using Spectral-Domain Optical Coherence Tomography (Spectralis SDOCT, Heidelberg Engineering GmbH, Germany) and the Retinal Function Imager (Optical Imaging, Ltd., Rehovot, Israel). Our results showed a higher FAZ area and diameter in MDR patients. Blood flow analysis also showed that there is a significantly smaller venous blood flow velocity in MDR patients. Also, a significant difference in roundness was observed between DM and MDR groups supporting the development of asymmetrical FAZ expansion with worsening DR. Our results suggest a potential anisotropy in the mechanical properties of the diabetic retina with no retinopathy that may trigger the FAZ elongation in a preferred direction resulting in either thinning or thickening of intraretinal layers in the inner and outer segments of the retina as a result of autoregulation. A detailed understanding of these relationships may facilitate earlier detection of DR, allowing for preservation of vision and better clinical outcomes. |*Regional Blood Flow [MESH] |Blood Flow Velocity [MESH] |Case-Control Studies [MESH] |Diabetes Mellitus/*physiopathology [MESH] |Diabetic Retinopathy/*physiopathology [MESH] |Female [MESH] |Humans [MESH] |Macula Lutea/*blood supply [MESH] |Male [MESH] |Middle Aged [MESH] |Retinal Vessels/*pathology/*physiopathology [MESH]Relationship between the morphology of the foveal avascular zone, reti(epmc).pdf DeepDyve Pubget Overpricing