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2017 ; 15
(4
): 500-506
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Diagnosis and treatment of anaphylaxis: there is an urgent needs to implement the
use of guidelines
#MMPMID29236793
Ribeiro MLKK
; Chong Neto HJ
; Rosario Filho NA
Einstein (Sao Paulo)
2017[Oct]; 15
(4
): 500-506
PMID29236793
show ga
Anaphylaxis is a severe, life-threatening generalized or systemic
hypersensitivity reaction that requires rapid and adequate care. This study aimed
to obtain an integrated view of the level of physicians' knowledge related with
treatment of anaphylaxis in studies published within the last 5 years. Sixteen
studies were found and four points were identified as of the great interest to
the authors: (1) emergency pharmacological treatment, (2) epinephrine
auto-injectors prescription, (3) knowledge of the main signs of anaphylaxis, and
(4) admission of the patient to verify biphasic reactions. Concern about the use
of intramuscular adrenaline as the first choice in relation with anaphylaxis was
evident in most studies, rather than its use in the comparison dial, and
especially low in a study that included data from Brazil, in which the frequency
of its use was 23.8%. An adrenaline autoinjector is highly recommended among
specialists for patients at risk of anaphylaxis, however, its use is still
infrequent among non-specialists and in countries that this agent is not
available. Intervention studies have shown improved medical knowledge of
anaphylaxis following disclosure of the information contained in the
international guidelines. The analysis of these studies reinforces the need to
disseminate international guidelines for diagnosis and treatment of anaphylaxis,
as well as providing an adrenaline autoinjector, to improve management and to
prevent a fatal outcome.