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2018 ; 2018
(ä): 5296168
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Characterization of Portuguese Centenarian Eating Habits, Nutritional Biomarkers,
and Cardiovascular Risk: A Case Control Study
#MMPMID29725498
da Silva AP
; Valente A
; Chaves C
; Matos A
; Gil A
; Santos AC
; Gorjão-Clara JP
; Bicho M
Oxid Med Cell Longev
2018[]; 2018
(ä): 5296168
PMID29725498
show ga
BACKGROUND AND AIMS: Eating habits may contribute to longevity. We characterized
the eating habits and cardiovascular risk (CVR) biomarkers in Portuguese
centenarians (CENT) compared to controls. METHODS AND RESULTS: Centenarians (n =
253), 100.26?±?1.98 years, were compared with 268 controls (67.51?±?3.25), low
(LCR) and high (HCR) CVR (QRISK®2-2016). Anthropometric and body composition were
evaluated by bioimpedance. Abdominal obesity, BMI, and fat mass (FM) cut-offs
were according to the WHO. Sarcopenia was defined by muscle mass index
cut-off???16.7?kg/m(2). Daily red meat intake, adjusted for age and gender, was
sarcopenia protective (OR?=?0.25, 95% CI?=?0.096-0.670, P = 0.006); however, it
contributes for FM excess (OR?=?4.946, 95% CI?=?1.471-16.626, P = 0.01),
overweight, and obesity (OR?=?4.804, 95% CI?=?1.666-13.851, P = 0.004). This
centenarian eating habit (2%) contrasts to HCR (64.3%). The history of red meat
(P < 0.0001) and canned/industrialized food intakes (P < 0.0001) was associated
with HCR. Basal metabolism was lower in centenarians versus LCR/HCR
(CENT?=?1176.78?±?201.98; LCR?=?1356.54?±?170.65; HCR?=?1561.33?±?267.85; P <
0.0001), BMI (CENT?=?21.06?±?3.68; LCR?=?28.49?±?4.69; HCR?=?29.56?±?5.26; P <
0.0001), waist circumference (CENT?=?85.29?±?10.83; LCR?=?96.02?±?11.71;
HCR?=?104.50?±?11.84; P < 0.0001), and waist-hip ratio (CENT?=?0.88?±?0.07;
LCR?=?0.92?±?0.08; HCR?=?1.01?±?0.08; P < 0.0001). CENT had lower total
cholesterol, LDL cholesterol, non-HDL cholesterol, and cholesterol/HDL ratio than
controls. CONCLUSIONS: Frequent consumption of red meat, cholesterol, and heme
iron rich may contribute to obesity and increased CVR. The low frequency of this
consumption, observed in centenarians, although associated with sarcopenia, may
be one of the keys to longevity.