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10.1126/science.aan6203

http://scihub22266oqcxt.onion/10.1126/science.aan6203
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C5872145!5872145!29051381
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suck abstract from ncbi


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pmid29051381      Science 2017 ; 358 (6361): 369-72
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  • Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus #MMPMID29051381
  • Khodagholy D; Gelinas JN; Buzsáki G
  • Science 2017[Oct]; 358 (6361): 369-72 PMID29051381show ga
  • Consolidation of declarative memories requires hippocampal-neocortical communication. Although experimental evidence supports the role of sharp-wave ripples in transferring hippocampal information to the neocortex, the exact cortical destinations and the physiological mechanisms of such transfer are not known. We used a conducting polymer-based conformable microelectrode array (NeuroGrid) to record local field potentials and neural spiking across the dorsal cortical surface of the rat brain, combined with silicon probe recordings in the hippocampus, to identify candidate physiological patterns. Parietal, midline, and prefrontal, but not primary cortical areas, displayed localized ripple (100 to 150 hertz) oscillations during sleep, concurrent with hippocampal ripples. Coupling between hippocampal and neocortical ripples was strengthened during sleep following learning. These findings suggest that ripple-ripple coupling supports hippocampal-association cortical transfer of memory traces.
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