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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Funct+Biomater 2018 ; 9 (1): ä Nephropedia Template TP
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Hydrogels for Hydrophobic Drug Delivery Classification, Synthesis and Applications #MMPMID29364833
Larraņeta E; Stewart S; Ervine M; Al-Kasasbeh R; Donnelly RF
J Funct Biomater 2018[Mar]; 9 (1): ä PMID29364833show ga
Hydrogels have been shown to be very useful in the field of drug delivery due to their high biocompatibility and ability to sustain delivery. Therefore, the tuning of their properties should be the focus of study to optimise their potential. Hydrogels have been generally limited to the delivery of hydrophilic drugs. However, as many of the new drugs coming to market are hydrophobic in nature, new approaches for integrating hydrophobic drugs into hydrogels should be developed. This article discusses the possible new ways to incorporate hydrophobic drugs within hydrogel structures that have been developed through research. This review describes hydrogel-based systems for hydrophobic compound delivery included in the literature. The section covers all the main types of hydrogels, including physical hydrogels and chemical hydrogels. Additionally, reported applications of these hydrogels are described in the subsequent sections.