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10.1111/tra.12552 http://scihub22266oqcxt.onion/10.1111/tra.12552 C5869154!5869154!29437282     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Traffic 2018 ; 19 (4): 273-84 Nephropedia Template TP {{tp|p=29437282|t=2018. Phagocytosis of antibody?opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages |pdf=|usr=}}{{29437282}} gab.com Text Phagocytosis of antibody opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages JO: Traffic http://www.kidney.de/pget.php?&tw=1&pmid=29437282 #FOAvip Despite the rapidly expanding use of antibody?based therapeutics to treat cancer, knowledge of the cellular processes following phagocytosis of antibody?opsonized tumor cells is limited. Here we report the formation of a phagosome?associated vacuole that is observed in macrophages as these degradative compartments mature following phagocytosis of HER2?positive cancer cells in the presence of the HER2?specific antibody, trastuzumab. We demonstrate that this vacuole is a distinct organelle that is closely apposed to the phagosome. Furthermore, the size of the phagosome?associated vacuole is increased by inhibition of the mTOR pathway. Collectively, the identification of this vacuolar compartment has implications for understanding the subcellular trafficking processes leading to the destruction of phagocytosed, antibody?opsonized cancer cells by macrophages. Twit Text FOAVip Phagocytosis of antibody opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages ????Traffic http://www.kidney.de/pget.php?&tw=1&pmid=29437282 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29437282 #FOAvip English Wikipedia <ref>{{Cite pmid|29437282}}</ref> Phagocytosis of antibody?opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages #MMPMID29437282 Velmurugan R; Ramakrishnan S; Kim M; Ober RJ; Ward ES Traffic 2018[Apr]; 19 (4): 273-84 PMID29437282show ga Despite the rapidly expanding use of antibody?based therapeutics to treat cancer, knowledge of the cellular processes following phagocytosis of antibody?opsonized tumor cells is limited. Here we report the formation of a phagosome?associated vacuole that is observed in macrophages as these degradative compartments mature following phagocytosis of HER2?positive cancer cells in the presence of the HER2?specific antibody, trastuzumab. We demonstrate that this vacuole is a distinct organelle that is closely apposed to the phagosome. Furthermore, the size of the phagosome?associated vacuole is increased by inhibition of the mTOR pathway. Collectively, the identification of this vacuolar compartment has implications for understanding the subcellular trafficking processes leading to the destruction of phagocytosed, antibody?opsonized cancer cells by macrophages. äPhagocytosis of antibody?opsonized tumor cells leads to the formation (epmc).pdf DeepDyve Pubget Overpricing