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10.3389/fonc.2018.00072 http://scihub22266oqcxt.onion/10.3389/fonc.2018.00072 C5868535!5868535!29616190     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Oncol 2018 ; 8 (ä): ä Nephropedia Template TP {{tp|p=29616190|t=2018. The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation |pdf=|usr=}}{{29616190}} gab.com Text The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation JO: Front Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29616190 #FOAvip Advancements in the early detection of cancer coupled with improved surgery, radiotherapy, and adjuvant therapy led to substantial increase in patient survival. Nevertheless, cancer metastasis is the leading cause of death in several cancer patients. The majority of these deaths are associated with metastatic relapse kinetics after a variable period of clinical remission. Most of the cancer recurrences are thought to be associated with the reactivation of dormant disseminated tumor cells (DTCs). In this review, we have summarized the cellular and molecular mechanisms related to DTCs and the role of microenvironmental niche. These mechanisms regulate the dormant state and help in the reactivation, which leads to metastatic outgrowth. Identification of novel therapeutic targets to eliminate these dormant tumor cells will be highly useful in controlling the metastatic relapse-related death with several cancers. Twit Text FOAVip The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation ????Front Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29616190 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29616190 #FOAvip English Wikipedia <ref>{{Cite pmid|29616190}}</ref> The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation #MMPMID29616190 Yadav AS; Pandey PR; Butti R; Radharani NNV; Roy S; Bhalara SR; Gorain M; Kundu GC; Kumar D Front Oncol 2018[]; 8 (ä): ä PMID29616190show ga Advancements in the early detection of cancer coupled with improved surgery, radiotherapy, and adjuvant therapy led to substantial increase in patient survival. Nevertheless, cancer metastasis is the leading cause of death in several cancer patients. The majority of these deaths are associated with metastatic relapse kinetics after a variable period of clinical remission. Most of the cancer recurrences are thought to be associated with the reactivation of dormant disseminated tumor cells (DTCs). In this review, we have summarized the cellular and molecular mechanisms related to DTCs and the role of microenvironmental niche. These mechanisms regulate the dormant state and help in the reactivation, which leads to metastatic outgrowth. Identification of novel therapeutic targets to eliminate these dormant tumor cells will be highly useful in controlling the metastatic relapse-related death with several cancers. äThe Biology and Therapeutic Implications of Tumor Dormancy and Reactiv(epmc).pdf DeepDyve Pubget Overpricing