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10.3390/genes9030159 http://scihub22266oqcxt.onion/10.3390/genes9030159 C5867880!5867880!29534016     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+(Basel) 2018 ; 9 (3): ä Nephropedia Template TP {{tp|p=29534016|t=2018. CD99: A Cell Surface Protein with an Oncojanus Role in Tumors |pdf=|usr=}}{{29534016}} gab.com Text CD99: A Cell Surface Protein with an Oncojanus Role in Tumors JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=29534016 #FOAvip The cell surface molecule CD99 has gained interest because of its involvement in regulating cell differentiation and adhesion/migration of immune and tumor cells. However, the molecule plays an intriguing and dual role in different cell types. In particular, it acts as a requirement for cell malignancy or as an oncosuppressor in tumors. In addition, the gene encodes for two different isoforms, which also act in opposition inside the same cell. This review highlights key studies focusing on the dual role of CD99 and its isoforms and discusses major critical issues, challenges, and strategies for overcoming those challenges. The review specifically underscores the properties that make the molecule an attractive therapeutic target and identifies new relationships and areas of study that may be exploited. The elucidation of the spatial and temporal control of the expression of CD99 in normal and tumor cells is required to obtain a full appreciation of this molecule and its signaling. Twit Text FOAVip CD99: A Cell Surface Protein with an Oncojanus Role in Tumors ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=29534016 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29534016 #FOAvip English Wikipedia <ref>{{Cite pmid|29534016}}</ref> CD99: A Cell Surface Protein with an Oncojanus Role in Tumors #MMPMID29534016 Manara MC; Pasello M; Scotlandi K Genes (Basel) 2018[Mar]; 9 (3): ä PMID29534016show ga The cell surface molecule CD99 has gained interest because of its involvement in regulating cell differentiation and adhesion/migration of immune and tumor cells. However, the molecule plays an intriguing and dual role in different cell types. In particular, it acts as a requirement for cell malignancy or as an oncosuppressor in tumors. In addition, the gene encodes for two different isoforms, which also act in opposition inside the same cell. This review highlights key studies focusing on the dual role of CD99 and its isoforms and discusses major critical issues, challenges, and strategies for overcoming those challenges. The review specifically underscores the properties that make the molecule an attractive therapeutic target and identifies new relationships and areas of study that may be exploited. The elucidation of the spatial and temporal control of the expression of CD99 in normal and tumor cells is required to obtain a full appreciation of this molecule and its signaling. äCD99: A Cell Surface Protein with an Oncojanus Role in Tumors (epmc).pdf DeepDyve Pubget Overpricing