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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Adv+Sci+(Weinh) 2018 ; 5 (3): ä Nephropedia Template TP
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Organelle Transplantation: Polymer Functionalization of Isolated Mitochondria for Cellular Transplantation and Metabolic Phenotype Alteration (Adv Sci 3/2018) #MMPMIDC5867122
Wu S; Zhang A; Li S; Chatterjee S; Qi R; Segura?Ibarra V; Ferrari M; Gupte A; Blanco E; Hamilton DJ
Adv Sci (Weinh) 2018[Mar]; 5 (3): ä PMIDC5867122show ga
Isolated mitochondria are polymerically functionalized for transplantation into metabolically compromised cells. In article number 1700530, Elvin Blanco, Dale J. Hamilton, and co?workers demonstrate that coating mitochondria with a dextran?triphenylphosphonium (TPP) conjugate results in longer functional survival of the organelle ex vivo, increased cellular uptake, and an enhanced shift in the metabolic phenotype of cells compared to uncoated mitochondria.