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10.3892/mmr.2017.7422 http://scihub22266oqcxt.onion/10.3892/mmr.2017.7422 C5865827!5865827!28901424     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Med+Rep 2017 ; 16 (5): 6729-35 Nephropedia Template TP {{tp|p=28901424|t=2017. Tumor suppressor microRNA-613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A |pdf=|usr=}}{{28901424}} gab.com Text Tumor suppressor microRNA-613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A JO: Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901424 #FOAvip MicroRNAs (miRNAs) are small non-coding RNAs which can serve as oncogenes or tumor suppressors in glioma. The present study aimed to investigate the expression of miR-613 in glioma. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect miR-613 in glioma cells and tissues and the relationship between miR-613 and vascular endothelial growth factor (VEGF) A was assessed using a luciferase reporter assay. In addition, glioma cells were transfected with miR-613 mimics and the mRNA and protein expression of VEGFA was detected using RT-qPCR and western blot analysis, respectively. The proliferative, invasive and tube formation capabilities of transfected cells were also assessed in vitro. Furthermore, a nude mouse tumor xenograft model was used to investigate the effects of miR-613 on tumor growth in vivo. The results of the present study demonstrated that the expression of miR-613 was decreased in glioma cell lines, and was associated with the grade of glioma. Ectopic expression of miR-613 markedly suppressed glioma cell proliferation and angiogenesis. Furthermore, the upregulation of miR-613 inhibited tumor angiogenesis and tumor growth in xenografted nude mice in vivo. VEGFA was demonstrated as a direct target of miR-613, as detected by western blot and luciferase reporter assays, and mediated miR-613 induced glioma cell proliferation and angiogenesis inhibition. Twit Text FOAVip Tumor suppressor microRNA-613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A ????Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901424 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28901424 #FOAvip English Wikipedia <ref>{{Cite pmid|28901424}}</ref> Tumor suppressor microRNA-613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A #MMPMID28901424 Yu X; Wang W Mol Med Rep 2017[Nov]; 16 (5): 6729-35 PMID28901424show ga MicroRNAs (miRNAs) are small non-coding RNAs which can serve as oncogenes or tumor suppressors in glioma. The present study aimed to investigate the expression of miR-613 in glioma. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect miR-613 in glioma cells and tissues and the relationship between miR-613 and vascular endothelial growth factor (VEGF) A was assessed using a luciferase reporter assay. In addition, glioma cells were transfected with miR-613 mimics and the mRNA and protein expression of VEGFA was detected using RT-qPCR and western blot analysis, respectively. The proliferative, invasive and tube formation capabilities of transfected cells were also assessed in vitro. Furthermore, a nude mouse tumor xenograft model was used to investigate the effects of miR-613 on tumor growth in vivo. The results of the present study demonstrated that the expression of miR-613 was decreased in glioma cell lines, and was associated with the grade of glioma. Ectopic expression of miR-613 markedly suppressed glioma cell proliferation and angiogenesis. Furthermore, the upregulation of miR-613 inhibited tumor angiogenesis and tumor growth in xenografted nude mice in vivo. VEGFA was demonstrated as a direct target of miR-613, as detected by western blot and luciferase reporter assays, and mediated miR-613 induced glioma cell proliferation and angiogenesis inhibition. äTumor suppressor microRNA-613 inhibits glioma cell proliferation, inva(epmc).pdf DeepDyve Pubget Overpricing