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10.3892/mmr.2017.7414 http://scihub22266oqcxt.onion/10.3892/mmr.2017.7414 C5865819!5865819 !28901400     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28901400 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Med+Rep 2017 ; 16 (5 ): 6512-6517 Nephropedia Template TP {{tp|p=28901400 |t=2017. Taurine alleviates lipopolysaccharide?induced liver injury by anti?inflammation and antioxidants in rats |pdf=|usr=}}{{28901400 }} gab.com Text Taurine alleviates lipopolysaccharide induced liver injury by anti inflammation and antioxidants in rats JO: Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901400 #FOAvip The aim of the present study was to investigate the protective effect of taurine on lipopolysaccharide (LPS)?induced liver injury and its mechanisms. Male rats were randomly divided into three groups: Normal saline, LPS model and taurine treatment. Experimental animals were treated with saline or taurine (dissolved in saline, 200 mg/kg/day) via intravenous injection. After 2 h, saline or LPS (0.5 mg/kg) was administrated via intraperitoneal injection. Markers of liver injury, pro?inflammatory cytokines and superoxide dismutase (SOD) activity were determined in plasma. Liver tissues were removed for morphological analysis and determination by western blot analysis. Taurine significantly reduced the elevation in the levels of LPS?induced aspartate transaminase and alanine transaminase and decreased the concentrations of LPS?induced inflammatory factors including tumor necrosis factor?? and interleukin?6. Taurine also increased the activity of SOD in serum and the expression of heme oxygenase?1 protein in liver tissue. Taurine pretreatment also reduced the elevated expression levels of LPS?induced cyclooxygenase?2, nuclear factor ?B and extracellular regulated protein kinase. The results from the present study demonstrated that taurine alleviates LPS?induced liver injury. The beneficial role of taurine may be associated with its reduction of pro?inflammatory response and oxidative stress. Twit Text FOAVip Taurine alleviates lipopolysaccharide induced liver injury by anti inflammation and antioxidants in rats ????Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901400 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28901400 #FOAvip English Wikipedia <ref>{{Cite pmid|28901400 }}</ref> Taurine alleviates lipopolysaccharide?induced liver injury by anti?inflammation and antioxidants in rats #MMPMID28901400 Liu Y ; Li F ; Zhang L ; Wu J ; Wang Y ; Yu H Mol Med Rep 2017[Nov]; 16 (5 ): 6512-6517 PMID28901400 show ga The aim of the present study was to investigate the protective effect of taurine on lipopolysaccharide (LPS)?induced liver injury and its mechanisms. Male rats were randomly divided into three groups: Normal saline, LPS model and taurine treatment. Experimental animals were treated with saline or taurine (dissolved in saline, 200 mg/kg/day) via intravenous injection. After 2 h, saline or LPS (0.5 mg/kg) was administrated via intraperitoneal injection. Markers of liver injury, pro?inflammatory cytokines and superoxide dismutase (SOD) activity were determined in plasma. Liver tissues were removed for morphological analysis and determination by western blot analysis. Taurine significantly reduced the elevation in the levels of LPS?induced aspartate transaminase and alanine transaminase and decreased the concentrations of LPS?induced inflammatory factors including tumor necrosis factor?? and interleukin?6. Taurine also increased the activity of SOD in serum and the expression of heme oxygenase?1 protein in liver tissue. Taurine pretreatment also reduced the elevated expression levels of LPS?induced cyclooxygenase?2, nuclear factor ?B and extracellular regulated protein kinase. The results from the present study demonstrated that taurine alleviates LPS?induced liver injury. The beneficial role of taurine may be associated with its reduction of pro?inflammatory response and oxidative stress. |Alanine Transaminase/metabolism [MESH] |Animals [MESH] |Antioxidants/*metabolism [MESH] |Aspartate Aminotransferases/metabolism [MESH] |Chemical and Drug Induced Liver Injury/*drug therapy/metabolism [MESH] |Cytokines/metabolism [MESH] |Heme Oxygenase-1/metabolism [MESH] |Inflammation/*drug therapy/metabolism [MESH] |Interleukin-6/metabolism [MESH] |Lipopolysaccharides/*pharmacology [MESH] |Liver/*drug effects/metabolism [MESH] |Male [MESH] |Malondialdehyde/metabolism [MESH] |NF-kappa B/metabolism [MESH] |Oxidation-Reduction/drug effects [MESH] |Oxidative Stress/drug effects [MESH] |Rats [MESH] |Rats, Sprague-Dawley [MESH] |Superoxide Dismutase/metabolism [MESH] |Taurine/*pharmacology [MESH]Taurine alleviates lipopolysaccharide?induced liver injury by anti?inf(epmc).pdf DeepDyve Pubget Overpricing