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10.3892/mmr.2017.7489 http://scihub22266oqcxt.onion/10.3892/mmr.2017.7489 C5865814!5865814!28901500     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Med+Rep 2017 ; 16 (5): 6459-66 Nephropedia Template TP {{tp|p=28901500|t=2017. Cell cycle and pluripotency: Convergence on octamer-binding transcription factor 4 |pdf=|usr=}}{{28901500}} gab.com Text Cell cycle and pluripotency: Convergence on octamer-binding transcription factor 4 JO: Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901500 #FOAvip Embryonic stem cells (ESCs) have unlimited expansion potential and the ability to differentiate into all somatic cell types for regenerative medicine and disease model studies. Octamer-binding transcription factor 4 (OCT4), encoded by the POU domain, class 5, transcription factor 1 gene, is a transcription factor vital for maintaining ESC pluripotency and somatic reprogramming. Many studies have established that the cell cycle of ESCs is featured with an abbreviated G1 phase and a prolonged S phase. Changes in cell cycle dynamics are intimately associated with the state of ESC pluripotency, and manipulating cell-cycle regulators could enable a controlled differentiation of ESCs. The present review focused primarily on the emerging roles of OCT4 in coordinating the cell cycle progression, the maintenance of pluripotency and the glycolytic metabolism in ESCs. Twit Text FOAVip Cell cycle and pluripotency: Convergence on octamer-binding transcription factor 4 ????Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28901500 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28901500 #FOAvip English Wikipedia <ref>{{Cite pmid|28901500}}</ref> Cell cycle and pluripotency: Convergence on octamer-binding transcription factor 4 #MMPMID28901500 She S; Wei Q; Kang B; Wang YJ Mol Med Rep 2017[Nov]; 16 (5): 6459-66 PMID28901500show ga Embryonic stem cells (ESCs) have unlimited expansion potential and the ability to differentiate into all somatic cell types for regenerative medicine and disease model studies. Octamer-binding transcription factor 4 (OCT4), encoded by the POU domain, class 5, transcription factor 1 gene, is a transcription factor vital for maintaining ESC pluripotency and somatic reprogramming. Many studies have established that the cell cycle of ESCs is featured with an abbreviated G1 phase and a prolonged S phase. Changes in cell cycle dynamics are intimately associated with the state of ESC pluripotency, and manipulating cell-cycle regulators could enable a controlled differentiation of ESCs. The present review focused primarily on the emerging roles of OCT4 in coordinating the cell cycle progression, the maintenance of pluripotency and the glycolytic metabolism in ESCs. äCell cycle and pluripotency: Convergence on octamer-binding transcript(epmc).pdf DeepDyve Pubget Overpricing