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2015 ; 41
(6
): 124-131
Nephropedia Template TP
gab.com Text
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English Wikipedia
Hantavirus pulmonary syndrome in Canada: An overview of clinical features,
diagnostics, epidemiology and prevention
#MMPMID29769944
Drebot MA
; Jones S
; Grolla A
; Safronetz D
; Strong JE
; Kobinger G
; Lindsay RL
Can Commun Dis Rep
2015[Jun]; 41
(6
): 124-131
PMID29769944
show ga
Hantavirus pulmonary syndrome is a disease caused by the inhalation of excreta
from infected deer mice. In Canada, the majority of hantavirus pulmonary syndrome
cases occur in the western provinces of British Columbia, Alberta, Saskatchewan
and Manitoba and the primary cause of the illness is the Sin Nombre virus. Only
one case of hantavirus pulmonary syndrome has been documented in eastern Canada
(Québec); however, Sin Nombre virus-infected deer mice have been identified
across the country. Although cases are rare (yearly case numbers range from zero
to 13 and the total number of confirmed cases in Canada now total 109), the
mortality rate among infected individuals is approximately 30%. The majority of
cases occur in the spring and early summer indicating seasonally-associated risk
factors for viral exposure. In 2013 and 2014, a substantial increase in the
number of hantavirus pulmonary syndrome cases was identified; however the cause
remains unclear. No antivirals or vaccines are currently available and treatment
is supportive. Public education, rodent control and the use of personal
protective measures are key to avoid infections in at-risk populations.