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The BC Glomerulonephritis Network: Improving Access and Reducing the Cost of
Immunosuppressive Treatments for Glomerular Diseases
#MMPMID29581884
Barbour S
; Lo C
; Espino-Hernandez G
; Gill J
; Levin A
Can J Kidney Health Dis
2018[]; 5
(?): 2054358118759551
PMID29581884
show ga
Glomerulonephritis (GN) is a common cause of end-stage renal disease in Canada
and worldwide, and results in significant health care resource utilization and
patient morbidity. However, GN has not been a traditional priority of provincial
renal health care organizations, despite the known benefits to health services
delivery and patient outcomes from integrated provincial care in other types of
chronic kidney disease. To address this deficiency, the British Columbia (BC)
Provincial Renal Agency created the BC GN Network in 2013 to coordinate
provincial GN health services delivery informed by robust population-level data
capture on all GN patients in the province via the BC GN Registry. This report
describes the use of the BC GN Network infrastructure to systematically develop
and evaluate a provincial GN drug formulary to improve patient and physician
access to evidence-based immunosuppressive treatments for GN in a cost-efficient
manner that successfully halted historical trends of increasing medication costs.
An example is provided of using the provincial infrastructure to implement and
subsequently evaluate an evidence-informed health policy of converting brand to
generic tacrolimus for the treatment of GN. The BC GN Network, including the
provincial drug formulary and data infrastructure, is an example of the benefits
of expanding the mandate of provincial renal health administrative organizations
to include the care of patients with GN, and constitutes a viable health delivery
model that can be implemented in other Canadian provinces to achieve similar
goals.
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