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10.1186/s12939-018-0748-6 http://scihub22266oqcxt.onion/10.1186/s12939-018-0748-6 C5863824!5863824!29566721     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Equity+Health 2018 ; 17 (ä): ä Nephropedia Template TP {{tp|p=29566721|t=2018. Barriers for conducting clinical trials in developing countries- a systematic review |pdf=|usr=}}{{29566721}} gab.com Text Barriers for conducting clinical trials in developing countries- a systematic review JO: Int J Equity Health http://www.kidney.de/pget.php?&tw=1&pmid=29566721 #FOAvip Background: Clinical trials for identification of efficient and effective new diagnostic and treatment modalities are needed to address disproportionately high burden of communicable (e.g., HIV/AIDS, tuberculosis, and malaria) and non-communicable diseases (e.g., diabetes) in developing countries. However, gross under-representation in global clinical trial platforms contributes to sustained health inequity in these countries. We reviewed the literature on barriers facing clinical researchers in developing countries for conducting clinical trials in their countries. Methods: Literature indexed in PubMed, Embase, CINAHL and Web of Science, WHO Global Health Library were searched. Grey literature was also searched. Search key words included barriers, challenges, clinical trials and developing countries. Articles within the scope of this review were appraised by two reviewers. Results: Ten studies, which are reported in 15 papers, were included in this review. Following critical review we identified five unifying themes for barriers. Barriers for conducting clinical trials included lack of financial and human capacity, ethical and regulatory system obstacles, lack of research environment, operational barriers and competing demands. Conclusion and recommendation: There were substantial barriers at system, organization and individual level. We propose that to address this problem, instituting a system for wider implementation of local investigator-initiated trials is warranted. These trials are more applicable to local populations because they build on local healthcare knowledge. They are more demand-led, influence policy and responsive to a country?s needs because they are driven by a local or national agenda. Electronic supplementary material: The online version of this article (10.1186/s12939-018-0748-6) contains supplementary material, which is available to authorized users. Twit Text FOAVip Barriers for conducting clinical trials in developing countries- a systematic review ????Int J Equity Health http://www.kidney.de/pget.php?&tw=1&pmid=29566721 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29566721 #FOAvip English Wikipedia <ref>{{Cite pmid|29566721}}</ref> Barriers for conducting clinical trials in developing countries- a systematic review #MMPMID29566721 Alemayehu C; Mitchell G; Nikles J Int J Equity Health 2018[]; 17 (ä): ä PMID29566721show ga Background: Clinical trials for identification of efficient and effective new diagnostic and treatment modalities are needed to address disproportionately high burden of communicable (e.g., HIV/AIDS, tuberculosis, and malaria) and non-communicable diseases (e.g., diabetes) in developing countries. However, gross under-representation in global clinical trial platforms contributes to sustained health inequity in these countries. We reviewed the literature on barriers facing clinical researchers in developing countries for conducting clinical trials in their countries. Methods: Literature indexed in PubMed, Embase, CINAHL and Web of Science, WHO Global Health Library were searched. Grey literature was also searched. Search key words included barriers, challenges, clinical trials and developing countries. Articles within the scope of this review were appraised by two reviewers. Results: Ten studies, which are reported in 15 papers, were included in this review. Following critical review we identified five unifying themes for barriers. Barriers for conducting clinical trials included lack of financial and human capacity, ethical and regulatory system obstacles, lack of research environment, operational barriers and competing demands. Conclusion and recommendation: There were substantial barriers at system, organization and individual level. We propose that to address this problem, instituting a system for wider implementation of local investigator-initiated trials is warranted. These trials are more applicable to local populations because they build on local healthcare knowledge. They are more demand-led, influence policy and responsive to a country?s needs because they are driven by a local or national agenda. Electronic supplementary material: The online version of this article (10.1186/s12939-018-0748-6) contains supplementary material, which is available to authorized users. äBarriers for conducting clinical trials in developing countries- a sys(epmc).pdf DeepDyve Pubget Overpricing