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10.1016/j.cub.2018.01.087 http://scihub22266oqcxt.onion/10.1016/j.cub.2018.01.087 C5863764!5863764!29526594     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Biol 2018 ; 28 (6): 948-954.e4 Nephropedia Template TP {{tp|p=29526594|t=2018. Memory Consolidation Is Linked to Spindle-Mediated Information Processing during Sleep |pdf=|usr=}}{{29526594}} gab.com Text Memory Consolidation Is Linked to Spindle-Mediated Information Processing during Sleep JO: Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=29526594 #FOAvip How are brief encounters transformed into lasting memories? Previous research has established the role of non-rapid eye movement (NREM) sleep, along with its electrophysiological signatures of slow oscillations (SOs) and spindles, for memory consolidation [1, 2, 3, 4]. In related work, experimental manipulations have demonstrated that NREM sleep provides a window of opportunity to selectively strengthen particular memory traces via the delivery of auditory cues [5, 6, 7, 8, 9, 10], a procedure known as targeted memory reactivation (TMR). It has remained unclear, however, whether TMR triggers the brain?s endogenous consolidation mechanisms (linked to SOs and/or spindles) and whether those mechanisms in turn mediate effective processing of mnemonic information. We devised a novel paradigm in which associative memories (adjective-object and adjective-scene pairs) were selectively cued during a post-learning nap, successfully stabilizing next-day retention relative to non-cued memories. First, we found that, compared to novel control adjectives, memory cues evoked an increase in fast spindles. Critically, during the time window of cue-induced spindle activity, the memory category linked to the verbal cue (object or scene) could be reliably decoded, with the fidelity of this decoding predicting the behavioral consolidation benefits of TMR. These results provide correlative evidence for an information processing role of sleep spindles in service of memory consolidation. Twit Text FOAVip Memory Consolidation Is Linked to Spindle-Mediated Information Processing during Sleep ????Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=29526594 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29526594 #FOAvip English Wikipedia <ref>{{Cite pmid|29526594}}</ref> Memory Consolidation Is Linked to Spindle-Mediated Information Processing during Sleep #MMPMID29526594 Cairney SA; Guttesen AáV; El Marj N; Staresina BP Curr Biol 2018[Mar]; 28 (6): 948-954.e4 PMID29526594show ga How are brief encounters transformed into lasting memories? Previous research has established the role of non-rapid eye movement (NREM) sleep, along with its electrophysiological signatures of slow oscillations (SOs) and spindles, for memory consolidation [1, 2, 3, 4]. In related work, experimental manipulations have demonstrated that NREM sleep provides a window of opportunity to selectively strengthen particular memory traces via the delivery of auditory cues [5, 6, 7, 8, 9, 10], a procedure known as targeted memory reactivation (TMR). It has remained unclear, however, whether TMR triggers the brain?s endogenous consolidation mechanisms (linked to SOs and/or spindles) and whether those mechanisms in turn mediate effective processing of mnemonic information. We devised a novel paradigm in which associative memories (adjective-object and adjective-scene pairs) were selectively cued during a post-learning nap, successfully stabilizing next-day retention relative to non-cued memories. First, we found that, compared to novel control adjectives, memory cues evoked an increase in fast spindles. Critically, during the time window of cue-induced spindle activity, the memory category linked to the verbal cue (object or scene) could be reliably decoded, with the fidelity of this decoding predicting the behavioral consolidation benefits of TMR. These results provide correlative evidence for an information processing role of sleep spindles in service of memory consolidation. äMemory Consolidation Is Linked to Spindle-Mediated Information Process(epmc).pdf DeepDyve Pubget Overpricing