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10.1038/s41598-018-22940-3 http://scihub22266oqcxt.onion/10.1038/s41598-018-22940-3 C5862898!5862898!29563585     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2018 ; 8 (ä): ä Nephropedia Template TP {{tp|p=29563585|t=2018. Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells |pdf=|usr=}}{{29563585}} gab.com Text Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29563585 #FOAvip In this article, we explore a non-canonical form of collective cell migration, displayed by the metastatic murine mammary carcinoma cell line 4T1. We show here that in sparsely plated 4T1 cells, E-cadherin levels are moderately reduced (~50%), leading to the development of collective migration, whereby cells translocate in loose clusters, interconnected by thin membrane tethers. Knocking down E-cadherin blocked tether formation in these cells, leading to enhancement of migration rate and, at the same time, to suppression of lung metastases formation in vivo, and inhibition of infiltration into fibroblast monolayers ex vivo. These findings suggest that the moderate E-cadherin levels present in wild-type 4T1 cells play a key role in promoting cancer invasion and metastasis. Twit Text FOAVip Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29563585 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29563585 #FOAvip English Wikipedia <ref>{{Cite pmid|29563585}}</ref> Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells #MMPMID29563585 Elisha Y; Kalchenko V; Kuznetsov Y; Geiger B Sci Rep 2018[]; 8 (ä): ä PMID29563585show ga In this article, we explore a non-canonical form of collective cell migration, displayed by the metastatic murine mammary carcinoma cell line 4T1. We show here that in sparsely plated 4T1 cells, E-cadherin levels are moderately reduced (~50%), leading to the development of collective migration, whereby cells translocate in loose clusters, interconnected by thin membrane tethers. Knocking down E-cadherin blocked tether formation in these cells, leading to enhancement of migration rate and, at the same time, to suppression of lung metastases formation in vivo, and inhibition of infiltration into fibroblast monolayers ex vivo. These findings suggest that the moderate E-cadherin levels present in wild-type 4T1 cells play a key role in promoting cancer invasion and metastasis. äDual role of E-cadherin in the regulation of invasive collective migra(epmc).pdf DeepDyve Pubget Overpricing