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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Cardiovasc+Pharmacol
2018 ; 71
(3
): 129-136
Nephropedia Template TP
gab.com Text
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English Wikipedia
Levosimendan in Acute and Advanced Heart Failure: An Appraisal of the Clinical
Database and Evaluation of Its Therapeutic Applications
#MMPMID28817484
Altenberger J
; Gustafsson F
; Harjola VP
; Karason K
; Kindgen-Milles D
; Kivikko M
; Malfatto G
; Papp Z
; Parissis J
; Pollesello P
; Pölzl G
; Tschöpe C
J Cardiovasc Pharmacol
2018[Mar]; 71
(3
): 129-136
PMID28817484
show ga
The use of inotropes for correcting hemodynamic dysfunction in patients with
congestive heart failure has been described over many decades. However, negative
or insufficient data have been collected regarding the effects of cardiac
glycosides, catecholamines, and phosphodiesterase inhibitors on quality of life
and survival. More recently, the calcium sensitizer and potassium channel-opener
levosimendan has been proposed as a safer inodilator than traditional agents in
some heart failure settings, such as advanced heart failure. At the 2017 annual
congress of the Heart Failure Association of the European Society of Cardiology
(Paris, April 30-May 2), a series of tutorials delivered by lecturers from 8
European countries examined how to use levosimendan safely and effectively in
acute and advanced heart failure. The proceedings of those tutorials have been
collated in this review to provide an expert perspective on the optimized use of
levosimendan in those settings.
|Acute Disease
[MESH]
|Cardiotonic Agents/adverse effects/*therapeutic use
[MESH]