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10.1002/prot.25260 http://scihub22266oqcxt.onion/10.1002/prot.25260 C5860664!5860664 !28160322     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28160322 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proteins 2017 ; 85 (5 ): 908-916 Nephropedia Template TP {{tp|p=28160322 |t=2017. ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes |pdf=|usr=}}{{28160322 }} gab.com Text ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes JO: Proteins http://www.kidney.de/pget.php?&tw=1&pmid=28160322 #FOAvip The ATLAS (Altered TCR Ligand Affinities and Structures) database (https://zlab.umassmed.edu/atlas/web/) is a manually curated repository containing the binding affinities for wild-type and mutant T cell receptors (TCRs) and their antigens, peptides presented by the major histocompatibility complex (pMHC). The database links experimentally measured binding affinities with the corresponding three dimensional (3D) structures for TCR-pMHC complexes. The user can browse and search affinities, structures, and experimental details for TCRs, peptides, and MHCs of interest. We expect this database to facilitate the development of next-generation protein design algorithms targeting TCR-pMHC interactions. ATLAS can be easily parsed using modeling software that builds protein structures for training and testing. As an example, we provide structural models for all mutant TCRs in ATLAS, built using the Rosetta program. Utilizing these structures, we report a correlation of 0.63 between experimentally measured changes in binding energies and our predicted changes. Proteins 2017; 85:908-916. © 2016 Wiley Periodicals, Inc. Twit Text FOAVip ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes ????Proteins http://www.kidney.de/pget.php?&tw=1&pmid=28160322 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28160322 #FOAvip English Wikipedia <ref>{{Cite pmid|28160322 }}</ref> ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes #MMPMID28160322 Borrman T ; Cimons J ; Cosiano M ; Purcaro M ; Pierce BG ; Baker BM ; Weng Z Proteins 2017[May]; 85 (5 ): 908-916 PMID28160322 show ga The ATLAS (Altered TCR Ligand Affinities and Structures) database (https://zlab.umassmed.edu/atlas/web/) is a manually curated repository containing the binding affinities for wild-type and mutant T cell receptors (TCRs) and their antigens, peptides presented by the major histocompatibility complex (pMHC). The database links experimentally measured binding affinities with the corresponding three dimensional (3D) structures for TCR-pMHC complexes. The user can browse and search affinities, structures, and experimental details for TCRs, peptides, and MHCs of interest. We expect this database to facilitate the development of next-generation protein design algorithms targeting TCR-pMHC interactions. ATLAS can be easily parsed using modeling software that builds protein structures for training and testing. As an example, we provide structural models for all mutant TCRs in ATLAS, built using the Rosetta program. Utilizing these structures, we report a correlation of 0.63 between experimentally measured changes in binding energies and our predicted changes. Proteins 2017; 85:908-916. © 2016 Wiley Periodicals, Inc. |*Databases, Factual [MESH] |*Mutation [MESH] |*Software [MESH] |Binding Sites [MESH] |Histocompatibility Antigens Class I/*chemistry/genetics/immunology [MESH] |Humans [MESH] |Internet [MESH] |Ligands [MESH] |Models, Molecular [MESH] |Peptides/*chemistry/immunology [MESH] |Protein Binding [MESH] |Protein Conformation [MESH] |Receptors, Antigen, T-Cell/*chemistry/genetics/immunology [MESH]ATLAS: A database linking binding affinities with structures for wild-(epmc).pdf DeepDyve Pubget Overpricing