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10.1111/imr.12526 http://scihub22266oqcxt.onion/10.1111/imr.12526 C5860639!5860639!28258691     free     free     free       Immunol+Rev 2017 ; 276 (1): 178-91 Nephropedia Template TP {{tp|p=28258691|t=2017. Viewing Siglecs through the lens of tumor immunology |pdf=|usr=}}{{28258691}} gab.com Text Viewing Siglecs through the lens of tumor immunology JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=28258691 #FOAvip Many Siglecs function as inhibitory receptors on innate and adaptive immune cells and may contribute to the attenuation of immune responses to tumors. Siglec 9 on neutrophils and Siglec 7 on NK cells are prominent examples of inhibitory Siglecs that can potentially dampen anti-tumor immunity. CD169 is a Siglec that may function as an adhesion molecule and a facilitator of the recognition and internalization of sialic acid decorated apoptotic bodies and exosomes derived from tumors. It can potentially contribute to both the attenuation as well as the facilitation of anti-tumor immunity. Siglecs have been best studied in the tumor context in animal models of cancer. Modulators of Siglec function are likely to be developed and investigated clinically in a cancer context over the next few years. Twit Text FOAVip Viewing Siglecs through the lens of tumor immunology ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=28258691 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28258691 #FOAvip English Wikipedia <ref>{{Cite pmid|28258691}}</ref> Viewing Siglecs through the lens of tumor immunology #MMPMID28258691 Fraschilla I; Pillai S Immunol Rev 2017[Mar]; 276 (1): 178-91 PMID28258691show ga Many Siglecs function as inhibitory receptors on innate and adaptive immune cells and may contribute to the attenuation of immune responses to tumors. Siglec 9 on neutrophils and Siglec 7 on NK cells are prominent examples of inhibitory Siglecs that can potentially dampen anti-tumor immunity. CD169 is a Siglec that may function as an adhesion molecule and a facilitator of the recognition and internalization of sialic acid decorated apoptotic bodies and exosomes derived from tumors. It can potentially contribute to both the attenuation as well as the facilitation of anti-tumor immunity. Siglecs have been best studied in the tumor context in animal models of cancer. Modulators of Siglec function are likely to be developed and investigated clinically in a cancer context over the next few years. äViewing Siglecs through the lens of tumor immunology (epmc).pdf DeepDyve Pubget Overpricing