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10.1039/c7sc00758b http://scihub22266oqcxt.onion/10.1039/c7sc00758b C5859728!5859728 !29619195     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29619195 &cmd=llinks): Failed to open stream: HTTP request failed! 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Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence |pdf=|usr=}}{{29619195 }} gab.com Text Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence JO: Chem Sci http://www.kidney.de/pget.php?&tw=1&pmid=29619195 #FOAvip Macromolecular crystallography suffers from two major issues: getting well-diffracting crystals and solving the phase problem inherent to large macromolecules. Here, we describe the first example of a lanthanide complex family named "crystallophore" (Xo4), which contributes to tackling both bottlenecks. This terbium complex, Tb-Xo4, is an appealing agent for biocrystallography, combining the exceptional phasing power of the Tb(iii) heavy atom with powerful nucleating properties, providing ready-to-use crystals for structure determination. Furthermore, protein/Tb-Xo4 co-crystals can be easily detected and discriminated from other crystalline by-products using luminescence. We demonstrate the potential of this additive for the crystallisation and structure determination of eight proteins, two of whose structures were unknown. Twit Text FOAVip Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence ????Chem Sci http://www.kidney.de/pget.php?&tw=1&pmid=29619195 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29619195 #FOAvip English Wikipedia <ref>{{Cite pmid|29619195 }}</ref> Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence #MMPMID29619195 Engilberge S ; Riobé F ; Di Pietro S ; Lassalle L ; Coquelle N ; Arnaud CA ; Pitrat D ; Mulatier JC ; Madern D ; Breyton C ; Maury O ; Girard E Chem Sci 2017[Sep]; 8 (9 ): 5909-5917 PMID29619195 show ga Macromolecular crystallography suffers from two major issues: getting well-diffracting crystals and solving the phase problem inherent to large macromolecules. Here, we describe the first example of a lanthanide complex family named "crystallophore" (Xo4), which contributes to tackling both bottlenecks. This terbium complex, Tb-Xo4, is an appealing agent for biocrystallography, combining the exceptional phasing power of the Tb(iii) heavy atom with powerful nucleating properties, providing ready-to-use crystals for structure determination. Furthermore, protein/Tb-Xo4 co-crystals can be easily detected and discriminated from other crystalline by-products using luminescence. We demonstrate the potential of this additive for the crystallisation and structure determination of eight proteins, two of whose structures were unknown. äCrystallophore: a versatile lanthanide complex for protein crystallogr(epmc).pdf DeepDyve Pubget Overpricing