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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Curr+Ophthalmol
2018 ; 30
(1
): 80-84
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Intravitreal bevacizumab as rescue therapy following treatment failure with laser
photocoagulation in retinopathy of prematurity
#MMPMID29564414
Kara C
; Hekimo?lu E
; Petriçli ?S
; Ak?l H
J Curr Ophthalmol
2018[Mar]; 30
(1
): 80-84
PMID29564414
show ga
PURPOSE: To evaluate the efficacy of intravitreal bevacizumab (IVB) in case of
treatment failure with laser photocoagulation in retinopathy of prematurity
(ROP). METHODS: A retrospective review of infants treated with IVB injection due
to treatment failure with laser photocoagulation was performed. The anatomical
results and complications were evaluated after treatment. RESULTS: 9 eyes of 6
premature infants with a mean gestational age of 26.8 ± 3.0 weeks (range,
23-32 w) and mean birth weight of 958 ± 319 g (range, 600-1400 g) were
identified. Six of the eyes had zone 1 disease, and all of these eyes were
classified as aggressive posterior ROP (APROP). Three of the eyes had zone 2
disease, and one of these eyes was classified as APROP, and the other two eyes
were classified as high-risk pre-threshold disease. All of the eyes showed
regression of the disease except one patient, both eyes of whom progressed to
stage 4A. None of the patients developed ocular and systemic complications at the
end of the six-month follow-up period. CONCLUSION: IVB could be an option in
patients with ROP in whom laser photocoagulation failed.