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10.1038/ki.2009.18

http://scihub22266oqcxt.onion/10.1038/ki.2009.18
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C5858198!5858198!19337216
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suck abstract from ncbi


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pmid19337216      Kidney+Int 2009 ; 75 (8): 769-71
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  • Regulation of renal arteriolar tone by adenosine: novel role for type 2 receptors #MMPMID19337216
  • Bell TD; Welch WJ
  • Kidney Int 2009[Apr]; 75 (8): 769-71 PMID19337216show ga
  • Tubuloglomerular feedback regulation of glomerular filtration rate (GFR) is mediated by adenosine, which acts on type 1 receptors in the afferent arteriole to increase resistance. However, new findings in isolated mouse tissue suggest that adenosine also dilates the efferent arteriole, which would reinforce the ability of adenosine to reduce GFR. This new information extends the concept that adenosine acts as a paracrine agent on both afferent and efferent arterioles.
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