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10.1186/s12883-018-1033-4 http://scihub22266oqcxt.onion/10.1186/s12883-018-1033-4 C5856376!5856376 !29544461     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29544461 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMC+Neurol 2018 ; 18 (1 ): 30 Nephropedia Template TP {{tp|p=29544461 |t=2018. Clinical and radiological factors associated with unfavorable outcome after intravenous thrombolysis in patients with mild ischemic stroke |pdf=|usr=}}{{29544461 }} gab.com Text Clinical and radiological factors associated with unfavorable outcome after intravenous thrombolysis in patients with mild ischemic stroke JO: BMC Neurol http://www.kidney.de/pget.php?&tw=1&pmid=29544461 #FOAvip BACKGROUND: A significant proportion of patients with mild ischemic stroke become disabled despite receiving intravenous thrombolytic therapy. The purpose of this study was to assess the clinical and radiological factors associated with unfavorable outcomes in patients with minor ischemic stroke that received intravenous recombinant tissue plasminogen activator (rt-PA) therapy. METHODS: We identified anterior circulation stroke patients with initial National Institutes of Health Stroke Scale (NIHSS) scores ?5 who received intravenous thrombolysis within 4.5 h of stroke onset and had pretreatment magnetic resonance (MR)/MR angiography using our prospective stroke database. We analyzed baseline characteristics, infarction patterns on diffusion-weighted imaging (DWI), and steno-occlusive lesions on MR angiography. Unfavorable outcome was defined as a modified Rankin Scale (mRS) score???2 at 90 days. Logistic regression was used to determine independent predictors of unfavorable outcomes. RESULTS: Among 121 patients (85 men; mean age, 63.4?±?11.3 years) included in this study, 46 (38%) had unfavorable outcomes at 90 days and DWI lesion patterns showing infarction in the deep middle cerebral artery (MCA) territory involving the perforating artery area was observed in 47 (38.8%) patients. On multivariable analysis, unfavorable outcomes at 90 days were associated with diabetes [odds ratio (OR), 3.41; 95% confidence interval (CI), 1.06-10.9; P?=?0.039), NIHSS score on admission (OR, 2.11; 95% CI, 1.35-3.30; P?=?0.001), and infarction in the deep MCA territory on DWI (OR, 4.19; 95% CI, 1.63-10.8; P?=?0.003). Lesions in the deep MCA territory was independently associated with early neurological deterioration (P?=?0.032). The patients without deep MCA territory infarction had a higher prevalence of cardiac embolism (P?=?0.009). CONCLUSIONS: Higher NIHSS scores, diabetes, and deep MCA territory infarction may be useful for predicting unfavorable outcomes in patients with minor stroke treated with intravenous rt-PA therapy. Twit Text FOAVip Clinical and radiological factors associated with unfavorable outcome after intravenous thrombolysis in patients with mild ischemic stroke ????BMC Neurol http://www.kidney.de/pget.php?&tw=1&pmid=29544461 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29544461 #FOAvip English Wikipedia <ref>{{Cite pmid|29544461 }}</ref> Clinical and radiological factors associated with unfavorable outcome after intravenous thrombolysis in patients with mild ischemic stroke #MMPMID29544461 Kim DH ; Lee DS ; Nah HW ; Cha JK BMC Neurol 2018[Mar]; 18 (1 ): 30 PMID29544461 show ga BACKGROUND: A significant proportion of patients with mild ischemic stroke become disabled despite receiving intravenous thrombolytic therapy. The purpose of this study was to assess the clinical and radiological factors associated with unfavorable outcomes in patients with minor ischemic stroke that received intravenous recombinant tissue plasminogen activator (rt-PA) therapy. METHODS: We identified anterior circulation stroke patients with initial National Institutes of Health Stroke Scale (NIHSS) scores ?5 who received intravenous thrombolysis within 4.5 h of stroke onset and had pretreatment magnetic resonance (MR)/MR angiography using our prospective stroke database. We analyzed baseline characteristics, infarction patterns on diffusion-weighted imaging (DWI), and steno-occlusive lesions on MR angiography. Unfavorable outcome was defined as a modified Rankin Scale (mRS) score???2 at 90 days. Logistic regression was used to determine independent predictors of unfavorable outcomes. RESULTS: Among 121 patients (85 men; mean age, 63.4?±?11.3 years) included in this study, 46 (38%) had unfavorable outcomes at 90 days and DWI lesion patterns showing infarction in the deep middle cerebral artery (MCA) territory involving the perforating artery area was observed in 47 (38.8%) patients. On multivariable analysis, unfavorable outcomes at 90 days were associated with diabetes [odds ratio (OR), 3.41; 95% confidence interval (CI), 1.06-10.9; P?=?0.039), NIHSS score on admission (OR, 2.11; 95% CI, 1.35-3.30; P?=?0.001), and infarction in the deep MCA territory on DWI (OR, 4.19; 95% CI, 1.63-10.8; P?=?0.003). Lesions in the deep MCA territory was independently associated with early neurological deterioration (P?=?0.032). The patients without deep MCA territory infarction had a higher prevalence of cardiac embolism (P?=?0.009). CONCLUSIONS: Higher NIHSS scores, diabetes, and deep MCA territory infarction may be useful for predicting unfavorable outcomes in patients with minor stroke treated with intravenous rt-PA therapy. |Administration, Intravenous [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Brain Ischemia/complications/diagnostic imaging/pathology [MESH] |Diffusion Magnetic Resonance Imaging [MESH] |Female [MESH] |Fibrinolytic Agents/*therapeutic use [MESH] |Humans [MESH] |Logistic Models [MESH] |Magnetic Resonance Angiography [MESH] |Male [MESH] |Middle Aged [MESH] |Prospective Studies [MESH] |Stroke/diagnostic imaging/*drug therapy/*pathology [MESH] |Thrombolytic Therapy/*methods [MESH] |Time Factors [MESH] |Tissue Plasminogen Activator/therapeutic use [MESH] |Tomography, X-Ray Computed [MESH]Clinical and radiological factors associated with unfavorable outcome (epmc).pdf DeepDyve Pubget Overpricing