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10.3390/ijms19020459

http://scihub22266oqcxt.onion/10.3390/ijms19020459
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C5855681!5855681!29401683
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suck abstract from ncbi

pmid29401683      Int+J+Mol+Sci 2018 ; 19 (2): ä
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  • Epigenetics and MicroRNAs in Cancer #MMPMID29401683
  • Ramassone A; Pagotto S; Veronese A; Visone R
  • Int J Mol Sci 2018[Feb]; 19 (2): ä PMID29401683show ga
  • The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional structure of the genome is exploited by cancer cells to promote tumorigenesis. This reprogramming occurs because of hereditable chromatin chemical modifications and the consequent formation of RNA-protein-DNA complexes that represent the principal actors of the epigenetic phenomena. In this regard, the deregulation of a transcribed non-coding RNA may be both cause and consequence of a cancer-related epigenetic alteration. This review summarizes recent findings that implicate microRNAs in the aberrant epigenetic regulation of cancer cells.
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