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10.3390/ijms19020450 http://scihub22266oqcxt.onion/10.3390/ijms19020450 C5855672!5855672 !29393911     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29393911 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2018 ; 19 (2 ): ä Nephropedia Template TP {{tp|p=29393911 |t=2018. The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression |pdf=|usr=}}{{29393911 }} gab.com Text The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29393911 #FOAvip Approximately sixty per cent of ovarian cancer patients die within the first five years of diagnosis due to recurrence associated with chemoresistance. The metzincin family of metalloproteinases is enzymes involved in matrix remodeling in response to normal physiological changes and diseased states. Recently, there has been a mounting awareness of these proteinases and their endogenous inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), as superb modulators of cellular communication and signaling regulating key biological processes in cancer progression. This review investigates the role of metzincins and their inhibitors in ovarian cancer. We propose that understanding the metzincins and TIMP biology in ovarian cancer may provide valuable insights in combating ovarian cancer progression and chemoresistance-mediated recurrence in patients. Twit Text FOAVip The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29393911 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29393911 #FOAvip English Wikipedia <ref>{{Cite pmid|29393911 }}</ref> The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression #MMPMID29393911 Escalona RM ; Chan E ; Kannourakis G ; Findlay JK ; Ahmed N Int J Mol Sci 2018[Feb]; 19 (2 ): ä PMID29393911 show ga Approximately sixty per cent of ovarian cancer patients die within the first five years of diagnosis due to recurrence associated with chemoresistance. The metzincin family of metalloproteinases is enzymes involved in matrix remodeling in response to normal physiological changes and diseased states. Recently, there has been a mounting awareness of these proteinases and their endogenous inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), as superb modulators of cellular communication and signaling regulating key biological processes in cancer progression. This review investigates the role of metzincins and their inhibitors in ovarian cancer. We propose that understanding the metzincins and TIMP biology in ovarian cancer may provide valuable insights in combating ovarian cancer progression and chemoresistance-mediated recurrence in patients. |*Gene Expression Regulation, Neoplastic [MESH] |ADAMTS Proteins/*genetics/metabolism [MESH] |Antineoplastic Agents/pharmacology [MESH] |Disease Progression [MESH] |Drug Resistance, Neoplasm/genetics [MESH] |Female [MESH] |Humans [MESH] |Matrix Metalloproteinases/*genetics/metabolism [MESH] |Neoplasm Recurrence, Local/drug therapy/*genetics/mortality/pathology [MESH] |Ovarian Neoplasms/drug therapy/*genetics/mortality/pathology [MESH] |Ovary/drug effects/metabolism/pathology [MESH] |Signal Transduction [MESH] |Survival Analysis [MESH]The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspec(epmc).pdf DeepDyve Pubget Overpricing