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10.1371/journal.pone.0193970 http://scihub22266oqcxt.onion/10.1371/journal.pone.0193970 C5854356!5854356 !29543836     free     free     free       PLoS+One 2018 ; 13 (3 ): e0193970 Nephropedia Template TP {{tp|p=29543836 |t=2018. Beware the intruder: Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo |pdf=|usr=}}{{29543836 }} gab.com Text Beware the intruder: Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29543836 #FOAvip Inflammation plays an important role in the pathogenesis of ischemic stroke including an acute and prolonged inflammatory process. The role of neutrophil granulocytes as first driver of the immune reaction from the blood site is under debate due to controversial findings. In bone marrow chimeric mice we were able to study the dynamics of tdTomato-expressing neutrophils and GFP-expressing microglia after photothrombosis using intravital two-photon microscopy. We demonstrate the infiltration of neutrophils into the brain parenchyma and confirm a long-lasting contact between neutrophils and microglia as well as an uptake of neutrophils by microglia clearing the brain from peripheral immune cells. Twit Text FOAVip Beware the intruder: Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29543836 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29543836 #FOAvip English Wikipedia <ref>{{Cite pmid|29543836 }}</ref> Beware the intruder: Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo #MMPMID29543836 Neumann J ; Henneberg S ; von Kenne S ; Nolte N ; Müller AJ ; Schraven B ; Görtler MW ; Reymann KG ; Gunzer M ; Riek-Burchardt M PLoS One 2018[]; 13 (3 ): e0193970 PMID29543836 show ga Inflammation plays an important role in the pathogenesis of ischemic stroke including an acute and prolonged inflammatory process. The role of neutrophil granulocytes as first driver of the immune reaction from the blood site is under debate due to controversial findings. In bone marrow chimeric mice we were able to study the dynamics of tdTomato-expressing neutrophils and GFP-expressing microglia after photothrombosis using intravital two-photon microscopy. We demonstrate the infiltration of neutrophils into the brain parenchyma and confirm a long-lasting contact between neutrophils and microglia as well as an uptake of neutrophils by microglia clearing the brain from peripheral immune cells. |Animals [MESH] |Brain/pathology [MESH] |Disease Models, Animal [MESH] |Female [MESH] |Granulocytes/pathology [MESH] |Inflammation/pathology [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Microglia/*pathology [MESH] |Neutrophil Infiltration/physiology [MESH] |Neutrophils/*pathology [MESH]Beware the intruder: Real time observation of infiltrated neutrophils (epmc).pdf DeepDyve Pubget Overpricing